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Difference between revisions of "Crohn's disease"
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| Image = Crohn's disease - colon - high mag.jpg | | Image = Crohn's disease - colon - high mag.jpg | ||
| Width = | | Width = | ||
| Caption = Crohn's disease. [[H&E stain]]. | | Caption = Crohn's disease. [[H&E stain]]. | ||
| Micro = | | Micro = | ||
| Subtypes = | | Subtypes = | ||
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| ClinDDx = [[infectious colitis]], [[ulcerative colitis]] | | ClinDDx = [[infectious colitis]], [[ulcerative colitis]] | ||
}} | }} | ||
'''Crohn's disease''', abbreviated as '''CD''', is a type of [[inflammatory bowel disease]]. It is the bread and butter of gastroenterology, and is often seen by pathologists. | '''Crohn's disease''', abbreviated as '''[[CD]]''', is a type of [[inflammatory bowel disease]]. It is the bread and butter of gastroenterology, and is often seen by pathologists. | ||
==General== | ==General== | ||
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**Definition: fat on more than 50% of the intestinal surface.<ref name=pmid15888774/> | **Definition: fat on more than 50% of the intestinal surface.<ref name=pmid15888774/> | ||
***''[[Libre Pathology|LP]]'' understands this as ''fat on 50% of the circumference''. | ***''[[Libre Pathology|LP]]'' understands this as ''fat on 50% of the circumference''. | ||
**DDx of creeping fat: [[ulcerative colitis]], sclerosing mesenteritis, mesenteric panniculitis, epiploic appendagitis, omental infarction, gastrointestinal complication a renal transplant, idiopathic segmental ureteritis.<ref name=pmid18815796/> | **DDx of creeping fat: [[ulcerative colitis]], sclerosing mesenteritis, mesenteric panniculitis, [[epiploic appendagitis]], omental infarction, gastrointestinal complication a renal transplant, idiopathic segmental ureteritis.<ref name=pmid18815796/> | ||
**Can be seen radiologically. | **Can be seen radiologically. | ||
*Cobblestone appearance -- may be described as such on endoscopy; due to edema. | *Cobblestone appearance -- may be described as such on endoscopy; due to edema. | ||