Difference between revisions of "Prostatic stromal sarcoma"
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'''Prostatic stromal sarcoma''' is a very rare [[malignant]] tumour that arises from the stroma of the prostate. | '''Prostatic stromal sarcoma''', abbreviated '''PSS''', is a very rare [[malignant]] tumour that arises from the stroma of the [[prostate gland]]. | ||
==General== | ==General== | ||
| Line 6: | Line 6: | ||
==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
*Atypical spindle cells. ( | *Atypical spindle cells. | ||
*Necrosis or increased mitotic activity.<ref name=pmid22388992>{{Cite journal | last1 = De Berardinis | first1 = E. | last2 = Busetto | first2 = GM. | last3 = Antonini | first3 = G. | last4 = Giovannone | first4 = R. | last5 = Di Placido | first5 = M. | last6 = Magliocca | first6 = FM. | last7 = Di Silverio | first7 = A. | last8 = Gentile | first8 = V. | title = Incidental prostatic stromal tumor of uncertain malignant potential (STUMP): histopathological and immunohistochemical findings. | journal = Urologia | volume = 79 | issue = 1 | pages = 65-8 | month = | year = 2012 | doi = 10.5301/RU.2012.9099 | PMID = 22388992 }}</ref> | |||
DDx: | DDx: | ||
*[[Prostatic stromal tumour of uncertain malignant potential]] (STUMP). | *[[Prostatic stromal tumour of uncertain malignant potential]] (STUMP). | ||
*[[Gastrointestinal stromal tumour]].<ref name=pmid19222892>{{cite journal |authors=de la Roza G, Naqvi A, Clark K |title=Gastrointestinal stromal tumors presenting as a prostatic mass |journal=Can J Urol |volume=16 |issue=1 |pages=4502–6 |date=February 2009 |pmid=19222892 |doi= |url=}}</ref> | |||
*Other [[sarcoma]]s. | *Other [[sarcoma]]s. | ||
*[[Carcinosarcoma]] of the prostate.<ref name=pmid17170745>{{Cite journal | last1 = Hansel | first1 = DE. | last2 = Herawi | first2 = M. | last3 = Montgomery | first3 = E. | last4 = Epstein | first4 = JI. | title = Spindle cell lesions of the adult prostate. | journal = Mod Pathol | volume = 20 | issue = 1 | pages = 148-58 | month = Jan | year = 2007 | doi = 10.1038/modpathol.3800676 | PMID = 17170745 }}</ref> | *[[Carcinosarcoma]] of the prostate.<ref name=pmid17170745>{{Cite journal | last1 = Hansel | first1 = DE. | last2 = Herawi | first2 = M. | last3 = Montgomery | first3 = E. | last4 = Epstein | first4 = JI. | title = Spindle cell lesions of the adult prostate. | journal = Mod Pathol | volume = 20 | issue = 1 | pages = 148-58 | month = Jan | year = 2007 | doi = 10.1038/modpathol.3800676 | PMID = 17170745 }}</ref> | ||
*[[Radiation changes]]. | *[[Radiation changes]]. | ||
*[[Sarcomatoid prostate carcinoma]] - classically has conventional prostate carcinoma, frequently postradiation treatment. | |||
===Images=== | ===Images=== | ||
www | <gallery> | ||
*[ | Image: Prostatic stromal sarcoma -- very low mag.jpg | PSS - very low mag. (WC) | ||
*[ | Image: Prostatic stromal sarcoma -- low mag.jpg | PSS - low mag. (WC) | ||
Image: Prostatic stromal sarcoma -- intermed mag.jpg | PSS - intermed. mag. (WC) | |||
Image: Prostatic stromal sarcoma -- high mag.jpg | PSS - high mag. (WC) | |||
Image: Prostatic stromal sarcoma - alt -- high mag.jpg | PSS - high mag. (WC) | |||
Image: Prostatic stromal sarcoma -- very high mag.jpg | PSS - very high mag. (WC) | |||
</gallery> | |||
====www==== | |||
*[https://www.nature.com/articles/3800676/figures/7 PSS (nature.com)].<ref name=pmid17170745/> | |||
*[https://www.nature.com/articles/3800676/figures/8 PSS - phyllodes-like (nature.com)].<ref name=pmid17170745/> | |||
==See also== | ==See also== | ||
*[[Prostate gland]]. | *[[Prostate gland]]. | ||
*[[Phyllodes tumour]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Genitourinary pathology]] | [[Category:Genitourinary pathology]] | ||
Latest revision as of 05:03, 24 May 2020
Prostatic stromal sarcoma, abbreviated PSS, is a very rare malignant tumour that arises from the stroma of the prostate gland.
General
- Very rare - case reports.
Microscopic
Features:
- Atypical spindle cells.
- Necrosis or increased mitotic activity.[1]
DDx:
- Prostatic stromal tumour of uncertain malignant potential (STUMP).
- Gastrointestinal stromal tumour.[2]
- Other sarcomas.
- Carcinosarcoma of the prostate.[3]
- Radiation changes.
- Sarcomatoid prostate carcinoma - classically has conventional prostate carcinoma, frequently postradiation treatment.
Images
PSS - very low mag. (WC)
PSS - low mag. (WC)
PSS - intermed. mag. (WC)
PSS - high mag. (WC)
PSS - high mag. (WC)
PSS - very high mag. (WC)
www
See also
References
- ↑ De Berardinis, E.; Busetto, GM.; Antonini, G.; Giovannone, R.; Di Placido, M.; Magliocca, FM.; Di Silverio, A.; Gentile, V. (2012). "Incidental prostatic stromal tumor of uncertain malignant potential (STUMP): histopathological and immunohistochemical findings.". Urologia 79 (1): 65-8. doi:10.5301/RU.2012.9099. PMID 22388992.
- ↑ de la Roza G, Naqvi A, Clark K (February 2009). "Gastrointestinal stromal tumors presenting as a prostatic mass". Can J Urol 16 (1): 4502–6. PMID 19222892.
- ↑ 3.0 3.1 3.2 Hansel, DE.; Herawi, M.; Montgomery, E.; Epstein, JI. (Jan 2007). "Spindle cell lesions of the adult prostate.". Mod Pathol 20 (1): 148-58. doi:10.1038/modpathol.3800676. PMID 17170745.