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''Small cell carcinoma, hypercalcemic type'', and ''small cell carcinoma of the ovary, hypercalcemic type'' redirect here. | ''Small cell carcinoma, hypercalcemic type'', and ''small cell carcinoma of the ovary, hypercalcemic type'' redirect here. | ||
A proposed name | A proposed name for this entity is ''malignant rhabdoid tumour of the ovary'', abbreviated ''MRTO''.<ref name=pmid24752781>{{Cite journal | last1 = Foulkes | first1 = WD. | last2 = Clarke | first2 = BA. | last3 = Hasselblatt | first3 = M. | last4 = Majewski | first4 = J. | last5 = Albrecht | first5 = S. | last6 = McCluggage | first6 = WG. | title = No small surprise - small cell carcinoma of the ovary, hypercalcaemic type, is a malignant rhabdoid tumour. | journal = J Pathol | volume = 233 | issue = 3 | pages = 209-14 | month = Jul | year = 2014 | doi = 10.1002/path.4362 | PMID = 24752781 }}</ref> | ||
==General== | ==General== | ||
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*Very rare. | *Very rare. | ||
*Most common undifferentiated ovarian malignancy in individuals less than 40 years old.<ref name=pmid24658002/> | *Most common undifferentiated ovarian malignancy in individuals less than 40 years old.<ref name=pmid24658002/> | ||
*Associated with SMARCA4 mutations - may be familial.<ref name=pmid24658002>{{cite journal |author=Witkowski L, Carrot-Zhang J, Albrecht S, ''et al.'' |title=Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type |journal=Nat. Genet. |volume=46 |issue=5 |pages=438–43 |year=2014 |month=May |pmid=24658002 |doi=10.1038/ng.2931 |url=}}</ref> | *Associated with SMARCA4 (BRG1) mutations - may be familial.<ref name=pmid24658002>{{cite journal |author=Witkowski L, Carrot-Zhang J, Albrecht S, ''et al.'' |title=Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type |journal=Nat. Genet. |volume=46 |issue=5 |pages=438–43 |year=2014 |month=May |pmid=24658002 |doi=10.1038/ng.2931 |url=}}</ref> | ||
==Microscopic== | ==Microscopic== |
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