Difference between revisions of "Kidney tumours"

Kidney tumours (view source)

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 *High mitotic rate.
 *[[Hobnail pattern]] - cell width smaller at basement membrane than free surface ??? <ref>{{Ref PBoD|1018}}</ref>
+==Renal medullary carcinoma==
+===General===
+*Rare.
+*Assoc. with sickle cell trait and sickle cell anemia.<ref name=pmid7528470>{{cite journal |author=Davis CJ, Mostofi FK, Sesterhenn IA |title=Renal medullary carcinoma. The seventh sickle cell nephropathy |journal=Am. J. Surg. Pathol. |volume=19 |issue=1 |pages=1–11 |year=1995 |month=January |pmid=7528470 |doi= |url=}}</ref>
+==Gross==
+*Well circumscribed.
+*Medulla.
+===Microscopic===
+Features:<ref name=pmid7528470/><ref name=pmid17643096>{{cite journal |author=Watanabe IC, Billis A, Guimarães MS, ''et al.'' |title=Renal medullary carcinoma: report of seven cases from Brazil |journal=Mod. Pathol. |volume=20 |issue=9 |pages=914–20 |year=2007 |month=September |pmid=17643096 |doi=10.1038/modpathol.3800934 |url=}}</ref>
+*Variable architecture:
+**[[Adenoid cystic carcinoma]]-like appearance:
+***Cystic spaces.
+**Yolk sac-like.
+**Tubular.
+*Desmoplastic stroma.
+*Inflammation:
+**Lymphocytes.
+**Neutrophils - margination in vessels.
+Kidney disease assoc. with sickle cell disorders:<ref name=pmid7528470/>
+*Papillary necrosis.
+*Nephrotic syndrome.
+*Renal infarction.
+*Pyelonephritis.
 =Pediatric=