Collagenous gastritis: Difference between revisions
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = | | Image = Collagenous gastritis H&E.jpg | ||
| Width = | | Width = | ||
| Caption = | | Caption = | ||
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'''Collagenous gastritis''' is an extremely rare pathology of the [[stomach]]. It is seen in children and adults. | '''Collagenous gastritis''' is an extremely rare pathology of the [[stomach]]. It is seen in children and adults. | ||
==General== | |||
*Very rare | *Very rare<ref name=pmid23363075>{{Cite journal | last1 = Jin | first1 = X. | last2 = Koike | first2 = T. | last3 = Chiba | first3 = T. | last4 = Kondo | first4 = Y. | last5 = Ara | first5 = N. | last6 = Uno | first6 = K. | last7 = Asano | first7 = N. | last8 = Iijima | first8 = K. | last9 = Imatani | first9 = A. | title = Collagenous gastritis. | journal = Dig Endosc | volume = 25 | issue = 5 | pages = 547-9 | month = Sep | year = 2013 | doi = 10.1111/j.1443-1661.2012.01391.x | PMID = 23363075 }}</ref> ~ 30 cases reported in world literature in 2009.<ref name=pmid19730387>{{Cite journal | last1 = Brain | first1 = O. | last2 = Rajaguru | first2 = C. | last3 = Warren | first3 = B. | last4 = Booth | first4 = J. | last5 = Travis | first5 = S. | title = Collagenous gastritis: reports and systematic review. | journal = Eur J Gastroenterol Hepatol | volume = 21 | issue = 12 | pages = 1419-24 | month = Dec | year = 2009 | doi = 10.1097/MEG.0b013e32832770fa | PMID = 19730387 }}</ref> | ||
===Clinical=== | |||
children:<ref name=pmid23538318> </ref> | children:<ref name=pmid23538318>{{Cite journal | last1 = Hijaz | first1 = NM. | last2 = Septer | first2 = SS. | last3 = Degaetano | first3 = J. | last4 = Attard | first4 = TM. | title = Clinical outcome of pediatric collagenous gastritis: case series and review of literature. | journal = World J Gastroenterol | volume = 19 | issue = 9 | pages = 1478-84 | month = Mar | year = 2013 | doi = 10.3748/wjg.v19.i9.1478 | PMID = 23538318 }}</ref> | ||
*Dyspepsia or anemia. | *Dyspepsia or anemia. | ||
*Chronic. | *Chronic. | ||
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*Associated with ''[[celiac sprue]]'' or ''[[collagenous colitis]]''. | *Associated with ''[[celiac sprue]]'' or ''[[collagenous colitis]]''. | ||
==Gross== | |||
* | *Discoloured depression - focal.<ref name=pmid23363075/> (???) | ||
==Microscopic== | |||
Features: | Features: | ||
*Band of eosinophilic material (collagen) expands superficial lamina propria.<ref name=pmid23363075/> | *Band of eosinophilic material (collagen) expands superficial lamina propria.<ref name=pmid23363075/> | ||
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*[[Signet ring cell carcinoma]]. | *[[Signet ring cell carcinoma]]. | ||
===Images=== | |||
<gallery> | |||
Image:Collagenous gastritis H&E.jpg|Collagenous gastritis - H&E staining, med. mag. (WC/MO) | |||
Image:Collagenous gastritis Masson trichrome.jpg|Collagenous gastritis - Masson trichrome, med. mag. (WC/MO) | |||
Image:Collagenous gastritis Sirius Red.jpg|Collagenous gastritis - Sirius Red, med. mag. (WC/MO) | |||
</gallery> | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602509/figure/F1/ Collagenous gastritis (nih.gov)].<ref name=pmid23363075/> | *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602509/figure/F1/ Collagenous gastritis (nih.gov)].<ref name=pmid23363075/> | ||
==Stains== | |||
*[[Trichrome stain]] - highlights collagen. | *[[Trichrome stain]] - highlights collagen. | ||