Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia: Difference between revisions
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*Usually women (15 of 19 cases<ref name=pmid17099078>{{Cite journal | last1 = Davies | first1 = SJ. | last2 = Gosney | first2 = JR. | last3 = Hansell | first3 = DM. | last4 = Wells | first4 = AU. | last5 = du Bois | first5 = RM. | last6 = Burke | first6 = MM. | last7 = Sheppard | first7 = MN. | last8 = Nicholson | first8 = AG. | title = Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia: an under-recognised spectrum of disease. | journal = Thorax | volume = 62 | issue = 3 | pages = 248-52 | month = Mar | year = 2007 | doi = 10.1136/thx.2006.063065 | PMID = 17099078 }}</ref>). | *Usually women (15 of 19 cases<ref name=pmid17099078>{{Cite journal | last1 = Davies | first1 = SJ. | last2 = Gosney | first2 = JR. | last3 = Hansell | first3 = DM. | last4 = Wells | first4 = AU. | last5 = du Bois | first5 = RM. | last6 = Burke | first6 = MM. | last7 = Sheppard | first7 = MN. | last8 = Nicholson | first8 = AG. | title = Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia: an under-recognised spectrum of disease. | journal = Thorax | volume = 62 | issue = 3 | pages = 248-52 | month = Mar | year = 2007 | doi = 10.1136/thx.2006.063065 | PMID = 17099078 }}</ref>). | ||
*Typically non-smokers (16 of 19 cases<ref name=pmid17099078/>). | *Typically non-smokers (16 of 19 cases<ref name=pmid17099078/>). | ||
*DIPNECH has been described in the context of [[multiple endocrine neoplasia 1]].<ref name=pmid17099078/> | |||
Clinical:<ref name=pmid26112453>{{Cite journal | last1 = Chauhan | first1 = A. | last2 = Ramirez | first2 = RA. | title = Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH) and the Role of Somatostatin analogs: A Case Series. | journal = Lung | volume = | issue = | pages = | month = Jun | year = 2015 | doi = 10.1007/s00408-015-9754-2 | PMID = 26112453 }}</ref> | Clinical:<ref name=pmid26112453>{{Cite journal | last1 = Chauhan | first1 = A. | last2 = Ramirez | first2 = RA. | title = Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH) and the Role of Somatostatin analogs: A Case Series. | journal = Lung | volume = | issue = | pages = | month = Jun | year = 2015 | doi = 10.1007/s00408-015-9754-2 | PMID = 26112453 }}</ref> | ||
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Notes: | Notes: | ||
*The ''Marchevsky and Walts'' definition is not universally accepted. | *The ''Marchevsky and Walts'' definition is not universally accepted. | ||
*WHO definition is vague. | *[[World Health Organization]] (WHO) definition is vague. | ||
==Gross== | ==Gross== | ||
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DDx: | DDx: | ||
*[[lung metastasis|Metastases]]. | *[[lung metastasis|Metastases to the lung]]. | ||
==Microscopic== | ==Microscopic== | ||