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Difference between revisions of "Pediatric kidney tumours"
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Pediatric kidney tumours (view source)
Revision as of 06:05, 11 September 2018
, 06:05, 11 September 2018→Molecular
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====Cellular==== | ====Cellular==== | ||
Features:<ref name=Ref_WMSP284>{{Ref WMSP|284}}</ref> | Features:<ref name=Ref_WMSP284>{{Ref WMSP|284}}</ref> | ||
*Plump cells with vesicular nuclei. | *Plump cells with [[vesicular nuclei]]. | ||
*Well-defined border. | *Well-defined border. | ||
*Mitotically active. | *Mitotically active. | ||
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===Molecular=== | ===Molecular=== | ||
Cellular mesoblastic nephroma: | Cellular mesoblastic nephroma:<ref name=pmid29683818>{{Cite journal | last1 = Rudzinski | first1 = ER. | last2 = Lockwood | first2 = CM. | last3 = Stohr | first3 = BA. | last4 = Vargas | first4 = SO. | last5 = Sheridan | first5 = R. | last6 = Black | first6 = JO. | last7 = Rajaram | first7 = V. | last8 = Laetsch | first8 = TW. | last9 = Davis | first9 = JL. | title = Pan-Trk Immunohistochemistry Identifies NTRK Rearrangements in Pediatric Mesenchymal Tumors. | journal = Am J Surg Pathol | volume = 42 | issue = 7 | pages = 927-935 | month = Jul | year = 2018 | doi = 10.1097/PAS.0000000000001062 | PMID = 29683818 }}</ref> | ||
*t(12:15)(p13;q25) ETV6/NTRK3. | *t(12:15)(p13;q25) ETV6/[[NTRK3]]. | ||
**Same [[translocation]] if found in ''[[infantile fibrosarcoma]]''. | **Same [[translocation]] if found in ''[[infantile fibrosarcoma]]''. | ||
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==Renal rhabdoid tumour== | ==Renal rhabdoid tumour== | ||
*[[AKA]] ''rhabdoid tumour of the kidney'', abbreviated ''RTK''. | *[[AKA]] ''rhabdoid tumour of the kidney'', abbreviated ''RTK''. | ||
{{Main|Renal rhabdoid tumour}} | |||
==Renal cell carcinoma== | ==Renal cell carcinoma== | ||