Difference between revisions of "TRK fusions"
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Revision as of 05:39, 11 September 2018
TRK fusions are seen in many solid tumours and have targeted drugs.
Genes:
- TRK1
- TRK2
- TRK3
The TRK genes are tyrosine kinase receptors.
Multiple fusion partners for each gene.
Association
- MASC.
- Secretory breast carcinoma.
Drugs
- Merestinib.
- Larotrectinib.
- Others.