Difference between revisions of "Neuroendocrine carcinoma of the prostate"

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#redirect [[Small cell carcinoma of the prostate gland]]
'''Neuroendocrine carcinoma of the prostate''' is a rare group of [[prostate cancer]]s that is hypothesized to evolve in the context androgen deprivation therapy.<ref name=pmid24705311>{{Cite journal  | last1 = Epstein | first1 = JI. | last2 = Amin | first2 = MB. | last3 = Beltran | first3 = H. | last4 = Lotan | first4 = TL. | last5 = Mosquera | first5 = JM. | last6 = Reuter | first6 = VE. | last7 = Robinson | first7 = BD. | last8 = Troncoso | first8 = P. | last9 = Rubin | first9 = MA. | title = Proposed morphologic classification of prostate cancer with neuroendocrine differentiation. | journal = Am J Surg Pathol | volume = 38 | issue = 6 | pages = 756-67 | month = Jun | year = 2014 | doi = 10.1097/PAS.0000000000000208 | PMID = 24705311 }}</ref>
 
It is subclassified as per Epstein ''et al.'':<ref name=pmid24705311/>
*Usual prostate adenocarcinoma with neuroendocrine differentiation.
*Adenocarcinoma with Paneth cell neuroendocrine differentiation.
*Carcinoid tumour of the prostate.
*[[Small cell carcinoma of the prostate gland]].
*Large cell neuroendocrine carcinoma of the prostate.
*Mixed (small and/or large cell) neuroendocrine carcinoma-acinar adenocarcinoma.
 
==IHC==
*[[PSA]] typically negative in NE carcinoma.
 
==See also==
*[[Prostate cancer]].
*[[Neuroendocrine carcinoma]].
 
==References==
{{Reflist|1}}
 
[[Category:Genitourinary pathology]]

Revision as of 16:27, 19 March 2018

Neuroendocrine carcinoma of the prostate is a rare group of prostate cancers that is hypothesized to evolve in the context androgen deprivation therapy.[1]

It is subclassified as per Epstein et al.:[1]

  • Usual prostate adenocarcinoma with neuroendocrine differentiation.
  • Adenocarcinoma with Paneth cell neuroendocrine differentiation.
  • Carcinoid tumour of the prostate.
  • Small cell carcinoma of the prostate gland.
  • Large cell neuroendocrine carcinoma of the prostate.
  • Mixed (small and/or large cell) neuroendocrine carcinoma-acinar adenocarcinoma.

IHC

  • PSA typically negative in NE carcinoma.

See also

References

  1. ↑ 1.0 1.1 Epstein, JI.; Amin, MB.; Beltran, H.; Lotan, TL.; Mosquera, JM.; Reuter, VE.; Robinson, BD.; Troncoso, P. et al. (Jun 2014). "Proposed morphologic classification of prostate cancer with neuroendocrine differentiation.". Am J Surg Pathol 38 (6): 756-67. doi:10.1097/PAS.0000000000000208. PMID 24705311.
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