Giant cell tumour of tendon sheath: Difference between revisions

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{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Giant cell tumour of the tendon sheath -- very high mag.jpg
| Width      =
| Caption    = GCT of tendon sheath. [[H&E stain]].
| Micro      = foam cells, multinucleated giant cells (may be scarce), +/-tendon, +/-hemosiderin-laden macrophages
| Subtypes  =
| LMDDx      = [[giant cell lesions]]
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      = circumscribed mass - yellow-brown to tan
| Grossing  =
| Site      = hand - classic site
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence =
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = good (benign), can be malignant (rare)
| Other      =
| ClinDDx    =
}}
'''Giant cell tumour of tendon sheath''' is a relatively common tumour of small [[joints]]. It is grouped with the [[chondro-osseous tumours]].  It is abbreviated '''GCT of tendon sheath'''.
'''Giant cell tumour of tendon sheath''' is a relatively common tumour of small [[joints]]. It is grouped with the [[chondro-osseous tumours]].  It is abbreviated '''GCT of tendon sheath'''.
''Fibroma of tendon sheath'' (abbreviated ''FTS'') redirect to this article.


==General==
==General==
*Can be thought of as the small joint version of [[diffuse tenosynovial giant-cell tumour]] ([[AKA]] ''PVNS'').<ref name=Ref_DCHH341>{{Ref DCHH|341}}</ref>
*Can be thought of as the small joint version of [[diffuse tenosynovial giant-cell tumour]] ([[AKA]] ''PVNS'').<ref name=Ref_DCHH341>{{Ref DCHH|341-2}}</ref>
*Rarely recur.
*Rarely recur.
*Classically afflicts the hand.<ref name=Ref_WMSP612>{{Ref WMSP|612}}</ref>
*Classically afflicts the hand.<ref name=Ref_WMSP612>{{Ref WMSP|612}}</ref>
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DDx:
DDx:
*[[Giant cell lesions]].
*[[Giant cell lesions]].
*Plexiform fibrohistiocytoma.{{fact}}
*Fibroma of tendon sheath (FTS) - if one believes it is a separate entity.<ref>{{Cite journal  | last1 = Heckert | first1 = R. | last2 = Bear | first2 = J. | last3 = Summers | first3 = T. | last4 = Frew | first4 = M. | last5 = Gwinn | first5 = D. | last6 = McKay | first6 = P. | title = Fibroma of the tendon sheath - a rare hand tumor. | journal = Pol Przegl Chir | volume = 84 | issue = 12 | pages = 651-6 | month = Dec | year = 2012 | doi = 10.2478/v10035-012-0107-z | PMID = 23399633 }}</ref>
**IHC suggests ''FTS'' and ''GCT of tendon sheath'' are one entity.<Ref name=pmid7777476>{{Cite journal  | last1 = Maluf | first1 = HM. | last2 = DeYoung | first2 = BR. | last3 = Swanson | first3 = PE. | last4 = Wick | first4 = MR. | title = Fibroma and giant cell tumor of tendon sheath: a comparative histological and immunohistological study. | journal = Mod Pathol | volume = 8 | issue = 2 | pages = 155-9 | month = Feb | year = 1995 | doi =  | PMID = 7777476 }}</ref>


===Images===
===Images===
<gallery>
Image: Giant cell tumour of the tendon sheath -- intermed mag.jpg | GCT of tendon sheath - intermed. mag. (WC)
Image: Giant cell tumour of the tendon sheath -- high mag.jpg | GCT of tendon sheath - high mag. (WC)
Image: Giant cell tumour of the tendon sheath -- very high mag.jpg | GCT of tendon sheath - very high mag. (WC)
</gallery>
<gallery>
<gallery>
Image:Giant_cell_tumor_of_tendon_sheath_histopathology%281%29.jpg | GCT of tendon sheath. (WC/KGH)
Image:Giant_cell_tumor_of_tendon_sheath_histopathology%281%29.jpg | GCT of tendon sheath. (WC/KGH)
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==Sign out==
==Sign out==
<pre>
Submitted as "Giant Cell Tumour Right Long Finger", Excision:
- Giant cell tumour of tendon sheath.
</pre>
===Block letters===
<pre>
<pre>
LESION, RIGHT INDEX FINGER, EXCISION:
LESION, RIGHT INDEX FINGER, EXCISION:
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====Alternate====
====Alternate====
The sections show histiocytes and rare multinucleated giant cells on a background of dense
The sections show histiocyte-like cells and rare multinucleated giant cells on a background of dense
connective tissue compatible with tendon. Hemosiderin-laden macrophages are present. No
connective tissue compatible with tendon. Hemosiderin-laden macrophages are present. No
nuclear atypia is apparent. No mitotic activity is apparent.
nuclear atypia is apparent. No mitotic activity is apparent.
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==See also==
==See also==
*[[Chondro-osseous tumours]].
*[[Chondro-osseous tumours]].
*[[Diffuse tenosynovial giant-cell tumour]].


==References==
==References==
Retrieved from "https://librepathology.org/wiki/Giant_cell_tumour_of_tendon_sheath"