Difference between revisions of "Oral pathology"

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Oral pathology (view source)

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Features:
Features:
*+/-Ulceration.<ref name=pmid2234878>{{Cite journal  | last1 = Hay | first1 = KD. | last2 = Greig | first2 = DE. | title = Propolis allergy: a cause of oral mucositis with ulceration. | journal = Oral Surg Oral Med Oral Pathol | volume = 70 | issue = 5 | pages = 584-6 | month = Nov | year = 1990 | doi =  | PMID = 2234878 }}</ref>
*+/-Ulceration.<ref name=pmid2234878>{{Cite journal  | last1 = Hay | first1 = KD. | last2 = Greig | first2 = DE. | title = Propolis allergy: a cause of oral mucositis with ulceration. | journal = Oral Surg Oral Med Oral Pathol | volume = 70 | issue = 5 | pages = 584-6 | month = Nov | year = 1990 | doi =  | PMID = 2234878 }}</ref>
Image:
*[http://lupusimages.com/browser/detail/2488/histopathology-hyperparakeratosis-with-interface-mucositis Interface mucositis with parakeratosis in lupus (lupusimages.com)].


=Odontogenic tumours and cysts=
=Odontogenic tumours and cysts=
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===General===
===General===
*Benign.
*Benign.
*Sexually transmitted.<ref name=Ref_HaNP246>{{Ref HaNP|426}}</ref>
*Sexually transmitted.<ref name=Ref_HaNP246>{{Ref HaNP|246}}</ref>
*Typically seen in young adults.
*Typically seen in young adults.


===Gross===
===Gross===
*Polypoid projection with a broad base.
*Polypoid projection with a broad base.
*Usually palate or labia.<ref name=Ref_HaNP246>{{Ref HaNP|426}}</ref>
*Usually palate or labia.<ref name=Ref_HaNP246>{{Ref HaNP|246}}</ref>


===Microscopic===
===Microscopic===
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*No hyperkeratosis.
*No hyperkeratosis.


DDx:<ref name=Ref_HaNP246>{{Ref HaNP|426}}</ref>
DDx:<ref name=Ref_HaNP246>{{Ref HaNP|246}}</ref>
*[[Squamous papilloma]] - thinner papillary projections, often branch.
*[[Squamous papilloma]] - thinner papillary projections, often branch.
*[[Verruca vulgaris]] - church spire-like projections, hyperkeratosis and parakeratosis.
*[[Verruca vulgaris]] - church spire-like projections, hyperkeratosis and parakeratosis.
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*[[AKA]] ''focal fibrous hyperplasia'', [[AKA]] ''peripheral ossifying fibroma, [[AKA]] ''fibroid epulis'' (old term), [[AKA]] ''fibroepithelial polyp''.<ref name=Ref_Sternberg5_775>{{Ref Sternberg5|775}}</ref>
*[[AKA]] ''focal fibrous hyperplasia'', [[AKA]] ''peripheral ossifying fibroma, [[AKA]] ''fibroid epulis'' (old term), [[AKA]] ''fibroepithelial polyp''.<ref name=Ref_Sternberg5_775>{{Ref Sternberg5|775}}</ref>
*[[AKA]] ''oral fibroma''.<ref>URL: [http://emedicine.medscape.com/article/1080948-overview#aw2aab6b3 http://emedicine.medscape.com/article/1080948-overview#aw2aab6b3]. Accessed on: 20 August 2012.</ref><ref name=Ref_HaNP240>{{Ref HaNP|240}}</ref>
*[[AKA]] ''oral fibroma''.<ref>URL: [http://emedicine.medscape.com/article/1080948-overview#aw2aab6b3 http://emedicine.medscape.com/article/1080948-overview#aw2aab6b3]. Accessed on: 20 August 2012.</ref><ref name=Ref_HaNP240>{{Ref HaNP|240}}</ref>
===General===
{{Main|Oral fibroma}}
*Most common oral cavity tumour.<ref name=Ref_HaNP240>{{Ref HaNP|240}}</ref>
*Female predominance (female:male = 2:1), usually 30-50 years old.<ref name=Ref_HaNP240>{{Ref HaNP|240}}</ref>
 
*Multiple oral fibromas may be seen in [[Cowden disease]].<ref name=pmid16878060>{{Cite journal  | last1 = Segura Saint-Gerons | first1 = R. | last2 = Ceballos Salobreña | first2 = A. | last3 = Toro Rojas | first3 = M. | last4 = Gándara Rey | first4 = JM. | title = Oral manifestations of Cowden's disease. Presentation of a clinical case. | journal = Med Oral Patol Oral Cir Bucal | volume = 11 | issue = 5 | pages = E421-4 | month = Aug | year = 2006 | doi =  | PMID = 16878060 }}</ref><ref name=pmid20137749>{{Cite journal  | last1 = Oliveira | first1 = MA. | last2 = Medina | first2 = JB. | last3 = Xavier | first3 = FC. | last4 = Magalhães | first4 = M. | last5 = Ortega | first5 = KL. | title = Cowden syndrome. | journal = Dermatol Online J | volume = 16 | issue = 1 | pages = 7 | month =  | year = 2010 | doi =  | PMID = 20137749 | URL = http://dermatology.cdlib.org/1601/case_reports/cowden/ortega.html }}</ref>
*Histologically similar to [[fibrous papule]].<ref name=pmid20421776>{{Cite journal  | last1 = Fernandez-Flores | first1 = A. | title = Solitary oral fibromas of the tongue show similar morphologic features to fibrous papule of the face: a study of 31 cases. | journal = Am J Dermatopathol | volume = 32 | issue = 5 | pages = 442-7 | month = Jul | year = 2010 | doi = 10.1097/DAD.0b013e3181c47142 | PMID = 20421776 }}</ref>
 
===Microscopic===
Features:<ref name=pmid20421776/>
*Fibrous stroma - '''key feature'''.
**"Very pink" at low power.
*+/-Collagen bundles, may be prominent.
*Prominent (dilated) vessels.
*Overlying (squamous) mucosa benign (flat).
**+/-Hyperkeratosis +/-focal ulceration.<ref name=Ref_HaNP240>{{Ref HaNP|240}}</ref>
 
===Sign out===
<pre>
TONGUE LESION, BIOPSY:
- FIBROMA.
</pre>


=Pigmented lesions of the oral cavity=
=Pigmented lesions of the oral cavity=
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*[[Odontogenic tumours and cysts]].
*[[Odontogenic tumours and cysts]].
*[[Tongue]].
*[[Tongue]].
*[[Tonsil]].


=References=
=References=
Michael
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