Talk:Colon

See also: Talk:Gastrointestinal tract polyps.

Normal 1

Microscopic description

A. The sections show normal small bowel mucosa with a benign lymphoid nodule.
B-G. The sections show normal colonic-type mucosa.

Final diagnosis

A-G. Terminal ileum, cecum, ascending colon, transverse colon, descending colon, sigmoid colon, rectum; biopsies (7x) - no pathologic diagnosis.

Normal 2

Microscopic description

A. The sections show normal small bowel mucosa with a benign lymphoid nodule.
B-G. The sections show normal colonic-type mucosa.

Final diagnosis

A. Terminal ileum, biopsy - no pathologic diagnosis.
B. Cecum, biopsy - no pathologic diagnosis.
C. Ascending colon, biopsy - no pathologic diagnosis.
D. Transverse colon, biopsy - no pathologic diagnosis.
E. Descending colon, biopsy - no pathologic diagnosis.
F. Sigmoid colon, biopsy - no pathologic diagnosis.
G. Rectum, biopsy - no pathologic diagnosis.

Rectal prolapse

Microscopic

The section shows benign fibromuscular hyperplasia of the lamina propria and submucosa. There is a mucosal erosion with reactive lymphoid hyperplasia characterized by germinal center formation. The germinal centers contain tingible-body macrophages.

Final diagnosis

A. Rectal polyp, biopsy - Benign fibromuscular hyperplasia and mucosal lymphoid hyperplasia with mucosal erosion.

Colitis

Microscopic

A. The sections show normal small bowel mucosa.
B. The sections show colonic-type mucosa with a mild lymphoplasmic inflammatory infiltrate and mild eosinophilia. There is no cryptitis and no crypt abscesses are identified. There is no architectural distortion. No granulomas are identified.
C. The sections show normal colonic-type mucosa.
D. The sections show colonic-type mucosa with a mild lymphoplasmic inflammatory infiltrate, mild eosinophilia and cryptitis. No crypt abscesses are identified. There is no architectural distortion. No granulomas are identified.
E. The sections show colonic-type mucosa with a mild lymphoplasmic inflammatory infiltrate, mild eosinophilia and cryptitis. Mild architectural distortion is present. No crypt abscesses are identified. No granulomas are identified.
F. The sections show granulation tissue and scant reactive colonic-type mucosa with abundant inflammatory cells, including, plasma cells, lymphocytes, neutrophils and eosinophils. Cryptitis, crypt destruction and crypt abscesses are present. No granulomas are identified. No dysplasia is identified.
G. The sections show colonic-type mucosa with a mild lymphoplasmic inflammatory infiltrate, mild eosinophilia and cryptitis. Mild-to-moderate architectural distortion is present. No crypt abscesses are identified. No granulomas are identified.
H. The sections show colonic-type mucosa with a mild lymphoplasmic inflammatory infiltrate, and mild eosinophilia. Mild-to-moderate architectural distortion is present. Many intraepithelial lymphocytes are present. No definite cryptitis is identified. No crypt abscesses are identified. No granulomas are identified.

Final diagnosis

A. Terminal ileum, biopsy - no pathology.
B. Cecum, biopsy - mild chronic colitis with mild eosinophilia.
C. Ascending colon, biopsy - no pathology.
D. Transverse colon, biopsy - mild focal active colitis with mild eosinophilia.
E. Descending colon, biopsy - mild active colitis with architectural changes.
F. Descending colon ("area of ulceration"), biopsy - severe active colitis with ulceration.
G. Sigmoid colon, biopsy - mild active colitis with architectural distortion.
H. Rectum, biopsy - mild chronic proctitis with possible mild acute proctitis.