CNS cytopathology: Difference between revisions
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# Round nuclei with vesicular chromatin and unapparent or small nucleoli | # Round nuclei with vesicular chromatin and unapparent or small nucleoli | ||
# Visible actin striations / stress filaments in cells (seen as pink straight lines) | # Visible actin striations / stress filaments in cells (seen as pink straight lines) | ||
<gallery> | |||
File:Meningioma cytologie.jpg | HE smear of a meningioma displaying typical whorl formations (WC/jensflorian) | |||
</gallery> | |||
===Metastatic carcinoma=== | ===Metastatic carcinoma=== | ||
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{{Main|Metastasis}} | {{Main|Metastasis}} | ||
*[http://moon.ouhsc.edu/kfung/JTY1/NeuroTest/_derived/Q92-Ans.htm_txt_SampleQ92.gif Squamous cell carcinoma (ouhsc.edu)].<ref>URL: [http://moon.ouhsc.edu/kfung/JTY1/NeuroTest/Q92-Ans.htm http://moon.ouhsc.edu/kfung/JTY1/NeuroTest/Q92-Ans.htm]. Accessed on: 3 November 2010.</ref> | *[http://moon.ouhsc.edu/kfung/JTY1/NeuroTest/_derived/Q92-Ans.htm_txt_SampleQ92.gif Squamous cell carcinoma (ouhsc.edu)].<ref>URL: [http://moon.ouhsc.edu/kfung/JTY1/NeuroTest/Q92-Ans.htm http://moon.ouhsc.edu/kfung/JTY1/NeuroTest/Q92-Ans.htm]. Accessed on: 3 November 2010.</ref> | ||
*[http://moon.ouhsc.edu/kfung/JTY1/NeuroTest/Images/SampleQ50.gif | *[http://moon.ouhsc.edu/kfung/JTY1/NeuroTest/Images/SampleQ50.gif Adenocarcinoma (ouhsc.edu)]. | ||
*[http://moon.ouhsc.edu/kfung/JTY1/NeuroTest/Images/SampleQ59.gif Small cell carcinoma (ouhsc.edu)]. | *[http://moon.ouhsc.edu/kfung/JTY1/NeuroTest/Images/SampleQ59.gif Small cell carcinoma (ouhsc.edu)]. | ||
===Metastatic melanoma=== | |||
*Occasionally large bi- or multinucleated cells | |||
*Discohesive cells | |||
*Large nucleoli | |||
*Pigmented tumor cells | |||
*Accompanied by tumor infiltrating lymphocytes | |||
<gallery> | |||
File:Melanoma_CNS_met_smear_HE.jpg | Melanoma smear prep (H&E) | |||
File:Melanoma - cytology field stain.jpg | |||
</gallery> | |||
===Metastatic lymphoma=== | |||
*Small round and blue cells | |||
===Glial tumors=== | |||
* Elongated cell processes | |||
* Cohesive growth | |||
* Often attached to vasculature | |||
<gallery> | |||
File:Pilocytic astrocytoma - smear - very high mag.jpg | Pilocytic astrocytoma smear preparation (H&E) | |||
</gallery> | |||
==Things that don't smear well== | ==Things that don't smear well== | ||