Fetal thrombotic vasculopathy: Difference between revisions
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'''Fetal thrombotic vasculopathy''', abbreviated ''FTV'', is characterized by thrombi in the fetus. In the context of a [[placenta]], it is thrombi in the fetal [[blood vessel]]s of the placenta. | '''Fetal thrombotic vasculopathy''', abbreviated '''FTV''', is characterized by thrombi in the fetus. In the context of a [[placenta]], it is thrombi in the fetal [[blood vessel]]s of the placenta. | ||
A large number of terms are used for this including:<ref name=pmid19237859>{{Cite journal | last1 = Marchetti | first1 = D. | last2 = Belviso | first2 = M. | last3 = Fulcheri | first3 = E. | title = A case of stillbirth: the importance of placental investigation in medico-legal practice. | journal = Am J Forensic Med Pathol | volume = 30 | issue = 1 | pages = 64-8 | month = Mar | year = 2009 | doi = 10.1097/PAF.0b013e318187387e | PMID = 19237859 }}</ref> | A large number of terms are used for this including:<ref name=pmid19237859>{{Cite journal | last1 = Marchetti | first1 = D. | last2 = Belviso | first2 = M. | last3 = Fulcheri | first3 = E. | title = A case of stillbirth: the importance of placental investigation in medico-legal practice. | journal = Am J Forensic Med Pathol | volume = 30 | issue = 1 | pages = 64-8 | month = Mar | year = 2009 | doi = 10.1097/PAF.0b013e318187387e | PMID = 19237859 }}</ref> '''fibrinous vasculosis''', '''fibromuscular sclerosis''' and '''fetal artery stem thrombosis'''. | ||
The multitude of terms reflects the confusion about this finding and that it has numerous etiologies.<ref name=pmid19237859/> | The multitude of terms reflects the confusion about this finding and that it has numerous etiologies.<ref name=pmid19237859/> | ||
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==General== | ==General== | ||
*May cause [[IUGR]]. | *May cause [[IUGR]]. | ||
*Associated with cerebral palsy and common in perinatal deaths.<ref name=pmid10414494>{{ | *Associated with cerebral palsy and common in perinatal deaths.<ref name=pmid10414494>{{Cite journal | last1 = Kraus | first1 = FT. | last2 = Acheen | first2 = VI. | title = Fetal thrombotic vasculopathy in the placenta: cerebral thrombi and infarcts, coagulopathies, and cerebral palsy. | journal = Hum Pathol | volume = 30 | issue = 7 | pages = 759-69 | month = Jul | year = 1999 | doi = | PMID = 10414494 }}</ref> | ||
*Mother may have a prothrombotic condition.<ref name=pmid24108664>{{Cite journal | last1 = Magnetti | first1 = F. | last2 = Bagna | first2 = R. | last3 = Botta | first3 = G. | last4 = Viano | first4 = A. | last5 = Dorati | first5 = G. | last6 = Raia | first6 = M. | last7 = Bertino | first7 = E. | last8 = Saracco | first8 = P. | title = Fetal Thrombotic Vasculopathy and Perinatal Thrombosis: Should all Placentas be Examined? | journal = Am J Perinatol | volume = | issue = | pages = | month = Oct | year = 2013 | doi = 10.1055/s-0033-1357267 | PMID = 24108664 }}</ref> | *Mother may have a prothrombotic condition.<ref name=pmid24108664>{{Cite journal | last1 = Magnetti | first1 = F. | last2 = Bagna | first2 = R. | last3 = Botta | first3 = G. | last4 = Viano | first4 = A. | last5 = Dorati | first5 = G. | last6 = Raia | first6 = M. | last7 = Bertino | first7 = E. | last8 = Saracco | first8 = P. | title = Fetal Thrombotic Vasculopathy and Perinatal Thrombosis: Should all Placentas be Examined? | journal = Am J Perinatol | volume = | issue = | pages = | month = Oct | year = 2013 | doi = 10.1055/s-0033-1357267 | PMID = 24108664 }}</ref> | ||
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===Images=== | ===Images=== | ||
Case 1: | |||
<gallery> | <gallery> | ||
Image: Fetal thrombotic vasculopathy - low mag.jpg | FTV - low mag. (WC) | Image: Fetal thrombotic vasculopathy - low mag.jpg | FTV - low mag. (WC) | ||
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Image: Fetal thrombotic vasculopathy - very high mag.jpg | FTV - very high mag. (WC) | Image: Fetal thrombotic vasculopathy - very high mag.jpg | FTV - very high mag. (WC) | ||
</gallery> | </gallery> | ||
Case 2: | |||
<gallery> | |||
Image: Fetal thrombotic vasculopathy -- low mag.jpg | FTV - low mag. (WC) | |||
Image: Fetal thrombotic vasculopathy -- intermed mag.jpg | FTV - intermed mag. (WC) | |||
Image: Fetal thrombotic vasculopathy - alt -- intermed mag.jpg | FTV - intermed mag. (WC) | |||
Image: Fetal thrombotic vasculopathy -- high mag.jpg | FTV - high mag. (WC) | |||
</gallery> | |||
www: | |||
*[http://jcp.bmj.com/content/61/12/1254/F8.large.jpg FTV (bmj.com)].<ref>URL: [http://jcp.bmj.com/content/61/12/1254.abstract http://jcp.bmj.com/content/61/12/1254.abstract]. Accessed on: 12 January 2011.</ref> | |||
*[http://gut.bmj.com/content/41/3/354/F3.large.jpg Thrombus - rat (bmj.com)].<ref>URL: [http://gut.bmj.com/content/41/3/354.full http://gut.bmj.com/content/41/3/354.full]. Accessed on: 12 January 2011.</ref> | |||
*[http://www.womenandinfants.org/fertilityandpregnancy/images/FTV.Fig.4a.jpg FTV - low mag. (womenandinfants.org)].<ref>URL: [http://www.womenandinfants.org/fertilityandpregnancy/current-topics-in-perinatal-pathology.cfm http://www.womenandinfants.org/fertilityandpregnancy/current-topics-in-perinatal-pathology.cfm]. Accessed on: 17 December 2012.</ref> | |||
*[http://www.womenandinfants.org/fertilityandpregnancy/images/FTV.Fig.4b.jpg FTV - high mag. (womenandinfants.org)]. | |||
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