Difference between revisions of "Giant cell cystitis"
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DDx: | DDx: | ||
*[[Radiation cystitis]] - history of radiation. | *[[Radiation cystitis]] - history of radiation, more atypical usually with nucleoli. | ||
*[[Sarcoma]] of the bladder or metastatic sarcoma. | *[[Sarcoma]] of the bladder or metastatic sarcoma - typically more cellular. | ||
*Sarcomatoid change in [[urothelial carcinoma]]. | *Sarcomatoid change in [[urothelial carcinoma]]. | ||
Revision as of 20:59, 2 November 2016
Giant cell cystitis is term used for a benign change of the mesenchymal cells of the urinary bladder lamina propria.
Giant cell cystitis is considered a misnomer as may be seen in an otherwise normal bladder.[1]
General
- Considered a common benign finding; not a clinical entity.[2]
Microscopic
Features:[3]
- Scattered atypical mesenchymal cells - mononuclear or multinucleated.
- +/-Nuclear hyperchromasia and/or lobulation.
- Absence of apparent mitotic activity.
DDx:
- Radiation cystitis - history of radiation, more atypical usually with nucleoli.
- Sarcoma of the bladder or metastatic sarcoma - typically more cellular.
- Sarcomatoid change in urothelial carcinoma.
See also
References
- ↑ Hameed, O.; Humphrey, PA. (Mar 2010). "Pseudoneoplastic mimics of prostate and bladder carcinomas.". Arch Pathol Lab Med 134 (3): 427-43. doi:10.1043/1543-2165-134.3.427. PMID 20196670.
- ↑ Amin, Mahul B. (2010). Diagnostic Pathology: Genitourinary (1st ed.). Amirsys. pp. 2:6. ISBN 978-1931884280.
- ↑ Amin, Mahul B.; Eble, John; Grignon, David; Srigley, John. (2013). Urological Pathology (1st ed.). Wolters Kluwer. pp. 305. ISBN 978-0781782814.