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Difference between revisions of "Adenocarcinoma of the urinary bladder"
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Adenocarcinoma of the urinary bladder (view source)
Revision as of 18:14, 2 November 2016
, 18:14, 2 November 2016no edit summary
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| LMDDx = [[urachal carcinoma]], invasive [[urothelial carcinoma]] with glandular differentiation, [[metastatic]] adenocarcinoma, direct extension of [[adenocarcinoma]] from an adjacent structure (esp. [[colorectal adenocarcinoma]]) | | LMDDx = [[urachal carcinoma]], invasive [[urothelial carcinoma]] with glandular differentiation, [[metastatic]] adenocarcinoma, direct extension of [[adenocarcinoma]] from an adjacent structure (esp. [[colorectal adenocarcinoma]]) | ||
| Stains = | | Stains = | ||
| IHC = CK7 +ve, CK20 +ve, CDX2 +ve (strong, diffuse), beta-catenin | | IHC = CK7 +ve, CK20 +ve, CDX2 +ve (strong, diffuse), beta-catenin -ve (nuclei -ve, membranes +ve) | ||
| EM = | | EM = | ||
| Molecular = | | Molecular = | ||
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**[[Prostatic adenocarcinoma]] - esp. [[ductal adenocarcinoma of the prostate]]. | **[[Prostatic adenocarcinoma]] - esp. [[ductal adenocarcinoma of the prostate]]. | ||
**[[Endometrioid endometrial adenocarcinoma]]. | **[[Endometrioid endometrial adenocarcinoma]]. | ||
*Tubular adenoma of the urinary tract.<ref name=pmid23664485>{{Cite journal | last1 = Kao | first1 = CS. | last2 = Epstein | first2 = JI. | title = Tubular adenoma of the urinary tract: a newly described entity. | journal = Hum Pathol | volume = 44 | issue = 9 | pages = 1890-4 | month = Sep | year = 2013 | doi = 10.1016/j.humpath.2013.02.017 | PMID = 23664485 }}</ref> | *[[Tubular adenoma of the urinary tract]].<ref name=pmid23664485>{{Cite journal | last1 = Kao | first1 = CS. | last2 = Epstein | first2 = JI. | title = Tubular adenoma of the urinary tract: a newly described entity. | journal = Hum Pathol | volume = 44 | issue = 9 | pages = 1890-4 | month = Sep | year = 2013 | doi = 10.1016/j.humpath.2013.02.017 | PMID = 23664485 }}</ref> | ||
===Images=== | ===Images=== | ||
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*CK20 +ve. | *CK20 +ve. | ||
*CDX2 +ve (strong, diffuse). | *CDX2 +ve (strong, diffuse). | ||
*Beta-catenin | *Beta-catenin -ve (negative nuclear staining, positive membranous staining). | ||
**[[Colorectal adenocarcinoma]] typically has nuclear staining ''and'' membranous staining. | **[[Colorectal adenocarcinoma]] typically has nuclear staining ''and'' membranous staining. | ||
*Thrombomodulin +ve/-ve (~60% of cases). | *Thrombomodulin +ve/-ve (~60% of cases). | ||