Difference between revisions of "Constrictive bronchiolitis"

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'''Constrictive_bronchiolitis''' is rare [[medical lung disease]].
'''Constrictive bronchiolitis''' is rare [[medical lung disease]]. It is also known as '''bronchiolitis obliterans''', '''obliterative broncholitis''',<ref name=pmid16493150/> and '''bronchiolitis obliterans syndrome''' (abbreviated '''BOS''').<ref name=pmid18707652>{{Cite journal  | last1 = Sato | first1 = M. | last2 = Keshavjee | first2 = S. | title = Bronchiolitis obliterans syndrome: alloimmune-dependent and -independent injury with aberrant tissue remodeling. | journal = Semin Thorac Cardiovasc Surg | volume = 20 | issue = 2 | pages = 173-82 | month =  | year = 2008 | doi = 10.1053/j.semtcvs.2008.05.002 | PMID = 18707652 }}</ref>


It is also known as '''bronchiolitis obliterans''', '''obliterative broncholitis''',<ref name=pmid16493150/> and '''bronchiolitis obliterans syndrome''' (abbreviated '''BOS''').<ref name=pmid18707652>{{Cite journal  | last1 = Sato | first1 = M. | last2 = Keshavjee | first2 = S. | title = Bronchiolitis obliterans syndrome: alloimmune-dependent and -independent injury with aberrant tissue remodeling. | journal = Semin Thorac Cardiovasc Surg | volume = 20 | issue = 2 | pages = 173-82 | month =  | year = 2008 | doi = 10.1053/j.semtcvs.2008.05.002 | PMID = 18707652 }}</ref>
It should '''not''' be confused with ''idiopathic [[bronchiolitis obliterans organizing pneumonia]] (BOOP)'', and old term for ''cryptogenic organizing pneumonia''.


==General==
==General==

Revision as of 02:41, 14 September 2016

Constrictive bronchiolitis is rare medical lung disease. It is also known as bronchiolitis obliterans, obliterative broncholitis,[1] and bronchiolitis obliterans syndrome (abbreviated BOS).[2]

It should not be confused with idiopathic bronchiolitis obliterans organizing pneumonia (BOOP), and old term for cryptogenic organizing pneumonia.

General

  • Not the same as (idiopathic) bronchiolitis obliterans organizing pneumonia (BOOP) - in short:
    • BOOP: clogs the airway, has Masson bodies, treated with steroids - good prognosis.
    • Constrictive bronchiolitis: fibrosis around airways, crappy prognosis.
  • No good treatment.
  • Progressive.

Etiology/associations:[1]

Microscopic

Features:[1]

  1. Bronchiolitis - mononuclear and neutrophilic.
    • May be minimal late in the disease.
  2. Fibrosis - submucosal and peribronchiolar.
    • Can be patchy.

Notes:

  • Bronchioles = noncartilagenous airways usu. < 2 mm in diameter.[1]

Images

Stains

  • Elastic trichrome - useful for delineation of obliterated bronchioles.

See also

References

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Visscher, DW.; Myers, JL. (2006). "Bronchiolitis: the pathologist's perspective.". Proc Am Thorac Soc 3 (1): 41-7. doi:10.1513/pats.200512-124JH. PMID 16493150. http://pats.atsjournals.org/cgi/content/full/3/1/41.
  2. ↑ Sato, M.; Keshavjee, S. (2008). "Bronchiolitis obliterans syndrome: alloimmune-dependent and -independent injury with aberrant tissue remodeling.". Semin Thorac Cardiovasc Surg 20 (2): 173-82. doi:10.1053/j.semtcvs.2008.05.002. PMID 18707652.
  3. ↑ 3.0 3.1 Chien, JW.; Duncan, S.; Williams, KM.; Pavletic, SZ. (Jan 2010). "Bronchiolitis obliterans syndrome after allogeneic hematopoietic stem cell transplantation-an increasingly recognized manifestation of chronic graft-versus-host disease.". Biol Blood Marrow Transplant 16 (1 Suppl): S106-14. doi:10.1016/j.bbmt.2009.11.002. PMID 19896545.
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