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Difference between revisions of "Apocrine carcinoma of the breast"
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Apocrine carcinoma of the breast (view source)
Revision as of 11:38, 8 September 2016
, 11:38, 8 September 2016no edit summary
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| IF = | | IF = | ||
| Gross = | | Gross = | ||
| Grossing = | | Grossing = [[breast grossing]] | ||
| Staging = [[breast cancer staging]] | |||
| Site = [[breast]] - see ''[[invasive breast cancer]]'' | | Site = [[breast]] - see ''[[invasive breast cancer]]'' | ||
| Assdx = | | Assdx = | ||
| Line 38: | Line 39: | ||
==Microscopic== | ==Microscopic== | ||
Features:<ref name=Ref_BP217>{{Ref BP|217}}</ref> | Features:<ref name=Ref_BP217>{{Ref BP|217}}</ref> | ||
*Prominent [[nucleoli]]. | *Prominent red [[nucleoli]]. | ||
**Often multiple.<ref>{{Cite journal | last1 = O'Malley | first1 = FP. | last2 = Bane | first2 = A. | title = An update on apocrine lesions of the breast. | journal = Histopathology | volume = 52 | issue = 1 | pages = 3-10 | month = Jan | year = 2008 | doi = 10.1111/j.1365-2559.2007.02888.x | PMID = 18171412 }}</ref> | **Often multiple.<ref>{{Cite journal | last1 = O'Malley | first1 = FP. | last2 = Bane | first2 = A. | title = An update on apocrine lesions of the breast. | journal = Histopathology | volume = 52 | issue = 1 | pages = 3-10 | month = Jan | year = 2008 | doi = 10.1111/j.1365-2559.2007.02888.x | PMID = 18171412 }}</ref> | ||
*Abundant granular eosinophilic cytoplasm. | *Abundant granular eosinophilic cytoplasm. | ||
| Line 63: | Line 64: | ||
==IHC== | ==IHC== | ||
Smaller tumours classically:<ref name=pmid16045781>{{Cite journal | last1 = Honma | first1 = N. | last2 = Takubo | first2 = K. | last3 = Akiyama | first3 = F. | last4 = Sawabe | first4 = M. | last5 = Arai | first5 = T. | last6 = Younes | first6 = M. | last7 = Kasumi | first7 = F. | last8 = Sakamoto | first8 = G. | title = Expression of GCDFP-15 and AR decreases in larger or node-positive apocrine carcinomas of the breast. | journal = Histopathology | volume = 47 | issue = 2 | pages = 195-201 | month = Aug | year = 2005 | doi = 10.1111/j.1365-2559.2005.02181.x | PMID = 16045781 }}</ref> | Smaller tumours classically:<ref name=pmid16045781>{{Cite journal | last1 = Honma | first1 = N. | last2 = Takubo | first2 = K. | last3 = Akiyama | first3 = F. | last4 = Sawabe | first4 = M. | last5 = Arai | first5 = T. | last6 = Younes | first6 = M. | last7 = Kasumi | first7 = F. | last8 = Sakamoto | first8 = G. | title = Expression of GCDFP-15 and AR decreases in larger or node-positive apocrine carcinomas of the breast. | journal = Histopathology | volume = 47 | issue = 2 | pages = 195-201 | month = Aug | year = 2005 | doi = 10.1111/j.1365-2559.2005.02181.x | PMID = 16045781 }}</ref> | ||
*AR +ve. | *[[Androgen receptor|AR]] +ve. | ||
*[[GCDFP-15]] +ve. | *[[GCDFP-15]] +ve. | ||
Usually:<ref name=Ref_BP217>{{Ref BP|217}}</ref> | Usually:<ref name=Ref_BP217>{{Ref BP|217}}</ref> | ||