Invasive micropapillary carcinoma of the breast: Difference between revisions

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{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Breast MicropapillaryCarcinoma Invasive 2 PA.JPG
| Width      =
| Caption    = Invasive micropapillary carcinoma. [[H&E stain]].
| Synonyms  =
| Micro      = small micropapillary tufts of tumour cells or tubuloalveolar structures, central '''avascular''' stromal core, lear spaces/clefting around the small clusters of tumor cells, +/-lymphovascular invasion
| Subtypes  =
| LMDDx      = IDC NST with micropapillary features, metastatic [[serous carcinoma]]
| Stains    =
| IHC        = [[EMA]] +ve (periphery of nests) - described as inside-out pattern
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  = [[breast grossing]]
| Staging    = [[breast cancer staging]]
| Site      = [[breast]] - see ''[[invasive breast cancer]]''
| Assdx      =
| Syndromes  =
| Clinicalhx =
| Signs      =
| Symptoms  =
| Prevalence = rare
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = poor
| Other      =
| ClinDDx    =
| Tx        = surgical excision
}}
'''Invasive micropapillary carcinoma of the breast''', also '''micropapillary carcinoma''', is a rare type of [[invasive breast cancer]].
'''Invasive micropapillary carcinoma of the breast''', also '''micropapillary carcinoma''', is a rare type of [[invasive breast cancer]].


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*Abundant finely granular cytoplasm.   
*Abundant finely granular cytoplasm.   
*Mucin cytoplasmic but not in the surrounding clear spaces.   
*Mucin cytoplasmic but not in the surrounding clear spaces.   
*Nuclear atypia is moderate or severe.   
*[[Nuclear atypia]] is moderate or severe.   
*Mixed(micropapillary + other) histological pattern common.
*Mixed(micropapillary + other) histological pattern common.
*Can show psamomma bodies or other calcifications.
*Can show [[psammoma bodies]] or other calcifications.


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