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==General== | ==General== | ||
*Renal cell carcinoma (RCC) is increased in ADPKD; however, it is thought to be due to the higher incidence of RCC in patients with (advanced) chronic kidney disease, rather than ADPKD.<ref name=pmid19446940>{{Cite journal | last1 = Nishimura | first1 = H. | last2 = Ubara | first2 = Y. | last3 = Nakamura | first3 = M. | last4 = Nakanishi | first4 = S. | last5 = Sawa | first5 = N. | last6 = Hoshino | first6 = J. | last7 = Suwabe | first7 = T. | last8 = Takemoto | first8 = F. | last9 = Nakagawa | first9 = M. | title = Renal cell carcinoma in autosomal dominant polycystic kidney disease. | journal = Am J Kidney Dis | volume = 54 | issue = 1 | pages = 165-8 | month = Jul | year = 2009 | doi = 10.1053/j.ajkd.2009.01.270 | PMID = 19446940 }}</ref> | |||
**In a series of 510 patients evaluated clinically, 10 were found to have renal cell carcinoma. Eight of the ten were seen on imaging and two were detected by pathology.<ref name=pmid19446940>{{Cite journal | last1 = Nishimura | first1 = H. | last2 = Ubara | first2 = Y. | last3 = Nakamura | first3 = M. | last4 = Nakanishi | first4 = S. | last5 = Sawa | first5 = N. | last6 = Hoshino | first6 = J. | last7 = Suwabe | first7 = T. | last8 = Takemoto | first8 = F. | last9 = Nakagawa | first9 = M. | title = Renal cell carcinoma in autosomal dominant polycystic kidney disease. | journal = Am J Kidney Dis | volume = 54 | issue = 1 | pages = 165-8 | month = Jul | year = 2009 | doi = 10.1053/j.ajkd.2009.01.270 | PMID = 19446940 }}</ref> | |||
===Etiology=== | ===Etiology=== | ||
*Mutation in ''PKD1'' gene or ''PKD2'' gene. | *Mutation in ''PKD1'' gene or ''PKD2'' gene. |
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