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Difference between revisions of "Cancer antigen 125"
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==Positive== | ==Positive== | ||
*[[ | *[[Ovarian carcinoma]] ~ 75% of cases.<ref name=pmid16224215/> | ||
*[[ | **[[Serous carcinoma of the ovary]] ~ 95% of cases.<ref name=pmid16224215/> | ||
*[[Pancreatic ductal adenocarcinoma]].<ref name=pmid27093451>{{Cite journal | last1 = Jiang | first1 = K. | last2 = Tan | first2 = E. | last3 = Sayegh | first3 = Z. | last4 = Centeno | first4 = B. | last5 = Malafa | first5 = M. | last6 = Coppola | first6 = D. | title = Cancer Antigen 125 (CA125, MUC16) Protein Expression in the Diagnosis and Progression of Pancreatic Ductal Adenocarcinoma. | journal = Appl Immunohistochem Mol Morphol | volume = | issue = | pages = | month = Apr | year = 2016 | doi = 10.1097/PAI.0000000000000368 | PMID = 27093451 }}</ref> | *[[Pancreatic ductal adenocarcinoma]].<ref name=pmid27093451>{{Cite journal | last1 = Jiang | first1 = K. | last2 = Tan | first2 = E. | last3 = Sayegh | first3 = Z. | last4 = Centeno | first4 = B. | last5 = Malafa | first5 = M. | last6 = Coppola | first6 = D. | title = Cancer Antigen 125 (CA125, MUC16) Protein Expression in the Diagnosis and Progression of Pancreatic Ductal Adenocarcinoma. | journal = Appl Immunohistochem Mol Morphol | volume = | issue = | pages = | month = Apr | year = 2016 | doi = 10.1097/PAI.0000000000000368 | PMID = 27093451 }}</ref> | ||
*[[Epithelioid sarcoma]] - reported.<ref name=pmid16740043>{{Cite journal | last1 = Lee | first1 = HI. | last2 = Kang | first2 = KH. | last3 = Cho | first3 = YM. | last4 = Lee | first4 = OJ. | last5 = Ro | first5 = JY. | title = Proximal-type epithelioid sarcoma with elevated serum CA 125: report of a case with CA 125 immunoreactivity. | journal = Arch Pathol Lab Med | volume = 130 | issue = 6 | pages = 871-4 | month = Jun | year = 2006 | doi = 10.1043/1543-2165(2006)130[871:PESWES]2.0.CO;2 | PMID = 16740043 }}</ref> | *[[Epithelioid sarcoma]] - reported.<ref name=pmid16740043>{{Cite journal | last1 = Lee | first1 = HI. | last2 = Kang | first2 = KH. | last3 = Cho | first3 = YM. | last4 = Lee | first4 = OJ. | last5 = Ro | first5 = JY. | title = Proximal-type epithelioid sarcoma with elevated serum CA 125: report of a case with CA 125 immunoreactivity. | journal = Arch Pathol Lab Med | volume = 130 | issue = 6 | pages = 871-4 | month = Jun | year = 2006 | doi = 10.1043/1543-2165(2006)130[871:PESWES]2.0.CO;2 | PMID = 16740043 }}</ref> | ||
==Usually negative== | |||
*[[Breast carcinoma]] ~15% of cases show weak focal positivity.<ref name=pmid16224215>{{Cite journal | last1 = Tornos | first1 = C. | last2 = Soslow | first2 = R. | last3 = Chen | first3 = S. | last4 = Akram | first4 = M. | last5 = Hummer | first5 = AJ. | last6 = Abu-Rustum | first6 = N. | last7 = Norton | first7 = L. | last8 = Tan | first8 = LK. | title = Expression of WT1, CA 125, and GCDFP-15 as useful markers in the differential diagnosis of primary ovarian carcinomas versus metastatic breast cancer to the ovary. | journal = Am J Surg Pathol | volume = 29 | issue = 11 | pages = 1482-9 | month = Nov | year = 2005 | doi = | PMID = 16224215 }}</ref> | |||
==See also== | ==See also== | ||