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'''Squamous metaplasia of the anus''' is a metaplastic change of the columnar epithelium. It can histologically mimic [[anal intraepithelial neoplasia]] (AIN), especially. [[high-grade squamous intraepithelial lesion]] (HSIL). | '''Squamous metaplasia of the anus''' is a metaplastic change of the columnar epithelium. It can histologically mimic [[anal intraepithelial neoplasia]] (AIN), especially. [[high-grade squamous intraepithelial lesion]] (HSIL). | ||
==General== | |||
*Present in the transformation zone between the columnar epithelium of the [[rectum]] and squamous epithelium of the [[anus]] - similar to the transformation zone of the [[uterine cervix]].<ref name=pmid20436833>{{Cite journal | last1 = Pineda | first1 = CE. | last2 = Welton | first2 = ML. | title = Management of anal squamous intraepithelial lesions. | journal = Clin Colon Rectal Surg | volume = 22 | issue = 2 | pages = 94-101 | month = May | year = 2009 | doi = 10.1055/s-0029-1223840 | PMID = 20436833 }}</ref> | |||
==Microscopic== | ==Microscopic== |
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