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Difference between revisions of "Cystitis glandularis"
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{{ Infobox external links | |||
| Name = Cystitis cystica et glandularis | |||
| EHVSC = 10173 | |||
| pathprotocols = | |||
| wikipedia = | |||
| pathoutlines = | |||
}} | |||
'''Cystitis glandularis''' is an uncommon type of inflammatory process that afflicts the [[urinary bladder]] ([[cystits]]) | |||
''Cystitis cystica et glandularis'' and ''pyelitis cystica et glandularis'' redirect to here. | |||
==General== | |||
*Benign.<ref name=pmid25202387>{{Cite journal | last1 = Yi | first1 = X. | last2 = Lu | first2 = H. | last3 = Wu | first3 = Y. | last4 = Shen | first4 = Y. | last5 = Meng | first5 = Q. | last6 = Cheng | first6 = J. | last7 = Tang | first7 = Y. | last8 = Wu | first8 = F. | last9 = Ou | first9 = R. | title = Cystitis glandularis: A controversial premalignant lesion. | journal = Oncol Lett | volume = 8 | issue = 4 | pages = 1662-1664 | month = Oct | year = 2014 | doi = 10.3892/ol.2014.2360 | PMID = 25202387 }}</ref> | |||
*Can be thought of as [[cystitis cystica]] with mucin-secreting cells lining the cystic spaces.<ref name=Ref_WMSP304>{{Ref WMSP|304}}</ref> | |||
*When seen in conjunction with ''cystitis cystica'' it is called ''cystitis cystica et glandularis''. | |||
Note: | |||
*There are case reports of ''urethritis glandularis'' - the same lesion in the [[urethra]].<ref name=pmid11104631>{{Cite journal | last1 = Chan | first1 = YM. | last2 = Ka-Leung Cheng | first2 = D. | last3 = Nga-Yin Cheung | first3 = A. | last4 = Yuen-Sheung Ngan | first4 = H. | last5 = Wong | first5 = LC. | title = Female urethral adenocarcinoma arising from urethritis glandularis. | journal = Gynecol Oncol | volume = 79 | issue = 3 | pages = 511-4 | month = Dec | year = 2000 | doi = 10.1006/gyno.2000.5968 | PMID = 11104631 }}</ref><ref name=pmid17825180>{{Cite journal | last1 = Yin | first1 = G. | last2 = Liu | first2 = YQ. | last3 = Gao | first3 = P. | last4 = Wang | first4 = XH. | title = Male urethritis glandularis: case report. | journal = Chin Med J (Engl) | volume = 120 | issue = 16 | pages = 1460-1 | month = Aug | year = 2007 | doi = | PMID = 17825180 }}</ref> | |||
==Microscopic== | |||
Features:<ref name=Ref_PBoD1028>{{Ref PBoD|1028}}</ref> | |||
*Nests of urothelium within the lamina propria with cyst formation, i.e. lumens are present. | |||
*Cyst lining cells are cuboidal and/or columnar epithelium. | |||
**Produce mucin. | |||
*+/-Goblet cells, i.e. intestinal metaplasia.<ref name=Ref_WMSP304>{{Ref WMSP|304}}</ref> | |||
Note: | |||
*Nests should '''not''' extend into the muscularis propria. | |||
===Images=== | |||
<gallery> | |||
Image: Cystitis cystica et glandularis -- very low mag.jpg | CCG - very low mag. | |||
Image: Cystitis cystica et glandularis -- low mag.jpg | CCG - low mag. | |||
Image: Cystitis cystica et glandularis - alt -- intermed mag.jpg | CCG - intermed mag. | |||
Image: Cystitis cystica et glandularis -- high mag.jpg | CCG - high mag. | |||
</gallery> | |||
www: | |||
*[http://www.webpathology.com/image.asp?n=2&Case=50 Cystitis glandularis (webpathology.com)]. | |||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2684385/figure/F0002/ Cystitis cystica et glandularis (nih.gov)]. | |||
==Sign out== | |||
<pre> | |||
URINARY BLADDER NECK, BIOPSY: | |||
- CYSTITIS CYSTICA ET GLANDULARIS. | |||
- NEGATIVE FOR MALIGNANCY. | |||
</pre> | |||
===Micro=== | |||
The sections show urothelial mucosa with bland nests within the lamina propria with cyst formation. The stroma is edematous and has a mixed inflammatory infiltrate consisting of plasma cells, eosinophils, lymphocytes and neutrophils. | |||
==See also== | |||
*[[Urothelium]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||