Unclassified renal cell carcinoma: Difference between revisions
Jump to navigation
Jump to search
No edit summary |
No edit summary |
||
| (6 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = | | Image = Unclassified_renal_cell_carcinoma_-_thyroid-like_and_clear_cell-like_--_low_mag.jpg | ||
| Width = | | Width = | ||
| Caption = | | Caption = Unclassified renal cell carcinoma with thyroid-like and clear cell-like areas. [[H&E stain]]. | ||
| Synonyms = | | Synonyms = | ||
| Micro = One of the following: (1) a combination of other RCC histologic types, (2) "non-identifiable" pattern/unrecognizable cell type (3) pure [[sarcomatoid RCC]] without an identifiable (epithelioid) RCC subtype | | Micro = One of the following: (1) a combination of other RCC histologic types, (2) "non-identifiable" pattern/unrecognizable cell type (3) pure [[sarcomatoid RCC]] without an identifiable (epithelioid) RCC subtype | ||
| Line 14: | Line 14: | ||
| IF = | | IF = | ||
| Gross = kidney mass | | Gross = kidney mass | ||
| Grossing = | | Grossing = [[partial nephrectomy grossing]], [[total nephrectomy for tumour grossing]] | ||
| Staging = [[kidney cancer staging]] | |||
| Site = [[kidney]] - see ''[[kidney tumours]]'' | | Site = [[kidney]] - see ''[[kidney tumours]]'' | ||
| Assdx = | | Assdx = | ||
| Line 56: | Line 57: | ||
*Retroperitoneal [[sarcoma]], e.g. [[pleomorphic undifferentiated sarcoma]]. | *Retroperitoneal [[sarcoma]], e.g. [[pleomorphic undifferentiated sarcoma]]. | ||
*Newly described renal tumour or emerging entity - see ''[[Vancouver classification]]''. | *Newly described renal tumour or emerging entity - see ''[[Vancouver classification]]''. | ||
*Collision tumour, e.g. [[urothelial carcinoma]] and identifiable [[renal cell carcinoma]]. | *[[Collision tumour]], e.g. [[urothelial carcinoma]] and identifiable [[renal cell carcinoma]]. | ||
===Images=== | |||
====Case 1==== | |||
<gallery> | |||
Image: Unclassified renal cell carcinoma - thyroid-like with myomatous stroma -- low mag.jpg | URCC - low mag. | |||
Image: Unclassified renal cell carcinoma - thyroid-like -- intermed mag.jpg | URCC - intermed. mag. | |||
Image: Unclassified renal cell carcinoma - thyroid-like -- high mag.jpg | URCC - high mag. | |||
Image: Unclassified renal cell carcinoma - thyroid-like and clear cell-like -- low mag.jpg | URCC - low mag. | |||
Image: Unclassified renal cell carcinoma - thyroid-like and clear cell-like -- intermed mag.jpg | URCC - intermed. mag. | |||
Image: Unclassified renal cell carcinoma - thyroid-like and clear cell-like - alt -- intermed mag.jpg | URCC - intermed. mag. | |||
Image: Unclassified renal cell carcinoma - mixed clear cell and thyroid-like -- low mag.jpg | URCC - low mag. | |||
Image: Unclassified renal cell carcinoma - mixed clear cell and thyroid-like -- intermed mag.jpg | URCC - intermed. mag. | |||
Image: Unclassified renal cell carcinoma - mixed clear cell and thyroid-like -- high mag.jpg | URCC - high mag. | |||
</gallery> | |||
====Case 2==== | |||
<gallery> | |||
Image: Unclassified renal cell carcinoma in BHD -- low mag.jpg | URCC in [[BHD]] - low mag. | |||
Image: Unclassified renal cell carcinoma in BHD -- intermed mag.jpg | URCC in [[BHD]] - intermed. mag. | |||
Image: Unclassified renal cell carcinoma in BHD -- high mag.jpg | URCC in BHD - high mag. | |||
Image: Unclassified renal cell carcinoma in BHD -- very high mag.jpg | URCC in BHD - very high mag. | |||
Image: Unclassified renal cell carcinoma in BHD - b -- intermed mag.jpg | URCC in BHD - intermed. mag. | |||
Image: Unclassified renal cell carcinoma in BHD - b -- high mag.jpg | URCC in BHD - high mag. | |||
Image: Unclassified renal cell carcinoma in BHD - b -- very high mag.jpg | URCC in BHD - very high mag. | |||
</gallery> | |||
==IHC== | ==IHC== | ||
*Pankeratin +ve. | *Pankeratin +ve. | ||
* | *[[PAX8]] +ve. | ||
*Vimentin +ve/-ve. | *Vimentin +ve/-ve. | ||
*p63 -ve.<ref>{{Cite journal | last1 = Carvalho | first1 = JC. | last2 = Thomas | first2 = DG. | last3 = McHugh | first3 = JB. | last4 = Shah | first4 = RB. | last5 = Kunju | first5 = LP. | title = p63, CK7, PAX8 and INI-1: an optimal immunohistochemical panel to distinguish poorly differentiated urothelial cell carcinoma from high-grade tumours of the renal collecting system. | journal = Histopathology | volume = 60 | issue = 4 | pages = 597-608 | month = Mar | year = 2012 | doi = 10.1111/j.1365-2559.2011.04093.x | PMID = 22260386 }}</ref> | *p63 -ve.<ref>{{Cite journal | last1 = Carvalho | first1 = JC. | last2 = Thomas | first2 = DG. | last3 = McHugh | first3 = JB. | last4 = Shah | first4 = RB. | last5 = Kunju | first5 = LP. | title = p63, CK7, PAX8 and INI-1: an optimal immunohistochemical panel to distinguish poorly differentiated urothelial cell carcinoma from high-grade tumours of the renal collecting system. | journal = Histopathology | volume = 60 | issue = 4 | pages = 597-608 | month = Mar | year = 2012 | doi = 10.1111/j.1365-2559.2011.04093.x | PMID = 22260386 }}</ref> | ||