Difference between revisions of "Gastric heterotopia of the duodenum"
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#Foveolar epithelium with gastric pits | #Foveolar epithelium with gastric pits | ||
#Foveolar epithelium only. | #Foveolar epithelium only. | ||
Clinical DDx:<ref name=pmid21242038/> | |||
*Duodenal polyp, duodenal ulcer, tumour/submucosal tumour, [[duodenal carcinoma]], and [[duodenitis]]. | |||
==Gross== | ==Gross== | ||
Revision as of 12:27, 3 May 2016
Gastric heterotopia of the duodenum is a relatively common finding of the duodenum.
General
- Common ~15% of cases in one series.[1]
- Probably not related to Helicobacter pylori.[2]
Can be subdivided into:[3]
- Foveolar epithelium with gastric pits
- Foveolar epithelium only.
Clinical DDx:[3]
- Duodenal polyp, duodenal ulcer, tumour/submucosal tumour, duodenal carcinoma, and duodenitis.
Gross
- Typically nodules/polyps.[4]
Microscopic
Features:
- Foveolar epithelium.
- Gastric glands - body-type or antral-type.
DDx:
- Foveolar metaplasia (isolated) - see chronic duodenitis.
- Foveolar gastric-type dysplasia.[5]
Images
GH - low mag. (WC)
GH - intermed. mag. (WC)
GH - high mag. (WC)
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DUODENUM, BIOPSY: - SMALL BOWEL MUCOSA WITH GASTRIC (BODY-TYPE) HETEROTOPIA. - NEGATIVE FOR SIGNIFICANT PATHOLOGY.
Alternate
DUODENUM, BIOPSY: - SMALL BOWEL MUCOSA AND BRUNNER'S GLANDS WITHIN NORMAL LIMITS. - GASTRIC HETEROTOPIA, BODY-TYPE MUCOSA.
See also
References
- ↑ 1.0 1.1 Terada, T. (2012). "Pathologic observations of the duodenum in 615 consecutive duodenal specimens: I. benign lesions.". Int J Clin Exp Pathol 5 (1): 46-51. PMID 22295146.
- ↑ Genta, RM.; Kinsey, RS.; Singhal, A.; Suterwala, S. (Nov 2010). "Gastric foveolar metaplasia and gastric heterotopia in the duodenum: no evidence of an etiologic role for Helicobacter pylori.". Hum Pathol 41 (11): 1593-600. doi:10.1016/j.humpath.2010.04.010. PMID 20656325.
- ↑ 3.0 3.1 Terada, T. (Mar 2011). "Heterotopic gastric mucosa of the gastrointestinal tract: a histopathologic study of 158 cases.". Pathol Res Pract 207 (3): 148-50. doi:10.1016/j.prp.2010.12.004. PMID 21242038.
- ↑ Shousha, S.; Spiller, RC.; Parkins, RA. (Jan 1983). "The endoscopically abnormal duodenum in patients with dyspepsia: biopsy findings in 60 cases.". Histopathology 7 (1): 23-34. PMID 6840712.
- ↑ Park, do Y.; Srivastava, A.; Kim, GH.; Mino-Kenudson, M.; Deshpande, V.; Zukerberg, LR.; Song, GA.; Lauwers, GY. (Apr 2008). "Adenomatous and foveolar gastric dysplasia: distinct patterns of mucin expression and background intestinal metaplasia.". Am J Surg Pathol 32 (4): 524-33. doi:10.1097/PAS.0b013e31815b890e. PMID 18300795.