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Difference between revisions of "Organizing pneumonia"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Organizing pneumonia -- low mag.jpg | |||
| Width = | |||
| Caption = Organizing pneumonia. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = distal airway disease -- airways plugged with organizing exudate (fluffy light-staining paucicellular regions with stellate cells); no hobnailing of pneumocytes; type 2 pneumocytes hyperplasia is absent | |||
| Subtypes = | |||
| LMDDx = [[diffuse alveolar damage]] (proliferative phase), [[bronchiolitis obliterans]]. | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[lung]] - ''[[diffuse lung diseases]]'' | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = dependent on underlying cause | |||
| Other = | |||
| ClinDDx = [[cryptogenic organizing pneumonia]], [[lung transplant pathology|transplant rejection]], infection ([[pneumonia]]), [[collagen vascular disease]], peri-tumour | |||
| Tx = dependent on underlying cause | |||
}} | |||
'''Organizing pneumonia''', abbreviated '''OP''', is a histologic pattern in [[lung pathology]]. It fits into the larger category of [[diffuse lung diseases]]. | '''Organizing pneumonia''', abbreviated '''OP''', is a histologic pattern in [[lung pathology]]. It fits into the larger category of [[diffuse lung diseases]]. | ||
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*Toxic injury. | *Toxic injury. | ||
*Infection. | *Infection. | ||
*Peri- | *Peri-tumour - in proximity to a space-occupying lesion (abscess, neoplasm). | ||
Note: | Note: | ||
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===Images=== | ===Images=== | ||
<gallery> | |||
Image: Organizing pneumonia -- very low mag.jpg | OP - very low mag. (WC/Nephron) | |||
Image: Organizing pneumonia -- low mag.jpg | OP - low mag. (WC/Nephron) | |||
Image: Organizing pneumonia - alt -- low mag.jpg | OP - low mag. (WC/Nephron) | |||
Image: Organizing pneumonia - alt - intermed mag.jpg | OP - intermed. mag. (WC/Nephron) | |||
Image: Organizing pneumonia -- intermed mag.jpg | OP - intermed. mag. (WC/Nephron) | |||
Image: Organizing pneumonia -- high mag.jpg | OP - high mag. (WC/Nephron) | |||
</gallery> | |||
===Masson body=== | |||
<gallery> | <gallery> | ||
Image:Masson_body_-_intermed_mag.jpg | Masson body - intermed. mag. (WC/Nephron) | Image:Masson_body_-_intermed_mag.jpg | Masson body - intermed. mag. (WC/Nephron) | ||
Image:Masson_body_-_high_mag.jpg | Masson body - high mag. (WC/Nephron) | |||
Image:Masson_body_-_very_high_mag.jpg | Masson body - very high mag. (WC/Nephron) | Image:Masson_body_-_very_high_mag.jpg | Masson body - very high mag. (WC/Nephron) | ||
</gallery> | </gallery> | ||
www: | www: | ||
*[http://casereports.bmj.com/content/2011/bcr.11.2010.3483.full BOOP (bmj.com)]. | *[http://casereports.bmj.com/content/2011/bcr.11.2010.3483.full BOOP (bmj.com)]. | ||
*[http://www.flickr.com/photos/pulmonary_pathology/4733384977/ Masson body (flickr.com)]. | *[http://www.flickr.com/photos/pulmonary_pathology/4733384977/ Masson body (flickr.com)]. | ||
*[https://www.flickr.com/photos/pulmonary_pathology/3734401023 Organizing pneumonia (flicker.com)]. | |||
==Sign out== | |||
<pre> | |||
Lung, Right Lower Lobe, Open Lung Biopsy: | |||
- Organizing pneumonia. | |||
- Emphysematous changes. | |||
- NEGATIVE for significant pulmonary fibrosis. | |||
- NEGATIVE for malignancy. | |||
Comment: | |||
There is no evidence of granulomatous disease. | |||
</pre> | |||
===Micro=== | |||
Organizing pneumonia with well-formed Masson bodies is seen subpleural and peribronchial. It is pathcy and mild. Significant fibrosis is absent. Eosinophils are not readily apparent. | |||
==See also== | ==See also== | ||