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Difference between revisions of "Seminoma"
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ITGCN --> GCNIS
(ITGCN --> GCNIS) |
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| Line 6: | Line 6: | ||
| Micro = fried egg-like cells (clear or eosinophilic cytoplasm, central nucleus), lymphocytic infiltrate (common), +/-[[syncytiotrophoblast]]s (rare), +/-granulomas (uncommon) | | Micro = fried egg-like cells (clear or eosinophilic cytoplasm, central nucleus), lymphocytic infiltrate (common), +/-[[syncytiotrophoblast]]s (rare), +/-granulomas (uncommon) | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[embryonal carcinoma]], [[ | | LMDDx = [[embryonal carcinoma]], [[GCNIS]] (ITGCN), [[mixed germ cell tumour]], [[granulomatous orchitis]], [[testicular scar]], [[atrophic testis]] | ||
| Stains = | | Stains = | ||
| IHC = OCT3 +ve, CD117 +ve, CD30 -ve | | IHC = OCT3 +ve, CD117 +ve, CD30 -ve | ||
| Line 15: | Line 15: | ||
| Grossing = [[Orchiectomy grossing]] | | Grossing = [[Orchiectomy grossing]] | ||
| Site = [[testis]] | | Site = [[testis]] | ||
| Assdx = [[ | | Assdx = [[GCNIS]] | ||
| Syndromes = | | Syndromes = | ||
| Clinicalhx = | | Clinicalhx = | ||
| Line 45: | Line 45: | ||
===Epidemiology & etiology=== | ===Epidemiology & etiology=== | ||
*Arises from ''[[ | *Arises from ''[[germ cell neoplasia in situ]]'' (GCNIS). | ||
==Gross== | ==Gross== | ||