Difference between revisions of "Ovary"
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*[[AKA]] ''[[peritoneal inclusion cyst]]''.{{fact}} | *[[AKA]] ''[[peritoneal inclusion cyst]]''.{{fact}} | ||
*[[AKA]] ''cortical inclusion cyst''.<ref name=pmid11207821>{{Cite journal | last1 = Feeley | first1 = KM. | last2 = Wells | first2 = M. | title = Precursor lesions of ovarian epithelial malignancy. | journal = Histopathology | volume = 38 | issue = 2 | pages = 87-95 | month = Feb | year = 2001 | doi = | PMID = 11207821 }}</ref>{{fact}} | *[[AKA]] ''cortical inclusion cyst''.<ref name=pmid11207821>{{Cite journal | last1 = Feeley | first1 = KM. | last2 = Wells | first2 = M. | title = Precursor lesions of ovarian epithelial malignancy. | journal = Histopathology | volume = 38 | issue = 2 | pages = 87-95 | month = Feb | year = 2001 | doi = | PMID = 11207821 }}</ref>{{fact}} | ||
*[[AKA]] ''surface epithelial inclusion cyst''. | |||
===General=== | ===General=== | ||
*May be found incidentally, e.g. during C-section. | *May be found incidentally, e.g. during C-section. | ||
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DDx: | DDx: | ||
*[[Serous cystadenoma of the ovary]]. | *[[Serous cystadenoma of the ovary]] - must be >=1 cm.<ref name=Ref_GP384>{{Ref GP|384}}</ref> | ||
Image: | Image: | ||
Revision as of 18:55, 7 March 2016
The ovary has a wealth of pathology. It has benign tumours and malignant ones. It is a significant part of gynecologic pathology.
Normal ovary
- Corpora albicans - pale/white body with lobulated contour.
- Involuted corpus luteum.
- Not seen pre-pubertal.
- Number increase with age.
- Ovarian follicles.
- Stroma - hyperchromatic - spindle morphology, whorling.
- If the cells have a round morphology... think about endometriosis.
Images
www:
Corpus albicans. (WC)
Cysts - overview
General
- Very common.
Most common:
- Serous cystadenoma.
- Usually uniloculated.
- Morphology: ciliated, columnar.
- Mucinous cystadenoma.
- Usually multiloculated.[1]
- Memory device: multiloculated = mucinous.
- Usually multiloculated.[1]
- Endometrioma (see endometriosis).
- Simple cyst.
- Corpus luteum cyst.
- Cancerous cyst (see ovarian cancer).
Notes:
- Epithelium is often lost in processing - may make interpretation challenging
- Ovarian surface epithelium (previously call germinal epithelium) - covers the ovary
Ovarian surface vs. mesothelium:
- Image: ovarian surface epithelium - endojournals.org.
- Image: mesothelium - internetattitude.com.
Specific benign diagnoses
Endometriosis
Main article: Endometriosis
Corpus luteum cyst
General
- Normal in childbearing age women.
Gross
- Classically yellow.
Microscopic
Features:
- Pseudocyst lined by stratified, pale staining (luteinized) cells.
- +/-Hemorrhagic centre.
Images:
Benign mesothelial inclusion cyst
- AKA mesothelial inclusion cyst.
- AKA peritoneal inclusion cyst.[citation needed]
- AKA cortical inclusion cyst.[4][citation needed]
- AKA surface epithelial inclusion cyst.
General
- May be found incidentally, e.g. during C-section.
Epidemiology:
- Associated with previous surgery.
Gross
Microscopic
Features:
- Benign mesothelium.
- Single layer of squamoid or cuboid mesothelial cells.[6]
DDx:
- Serous cystadenoma of the ovary - must be >=1 cm.[7]
Image:
IHC
- CK +ve, calretinin +ve.[6]
Sign out
OVARY, LEFT, BIOPSY: - BENIGN CORTICAL INCLUSION CYST.
Ovarian infarct
Main article: Ovarian infarct
Pregnancy luteoma
Main article: Pregnancy luteoma
Ovarian tumours
Main article: Ovarian tumours
For a very brief overview of gynecologic tumours see: Gynecologic pathology.
See also
References
- ↑ IAV. 6 February 2009.
- ↑ Auersperg N, Wong AS, Choi KC, Kang SK, Leung PC (April 2001). "Ovarian surface epithelium: biology, endocrinology, and pathology". Endocr. Rev. 22 (2): 255–88. PMID 11294827. http://edrv.endojournals.org/cgi/pmidlookup?view=long&pmid=11294827.
- ↑ ALS. 5 February 2009.
- ↑ Feeley, KM.; Wells, M. (Feb 2001). "Precursor lesions of ovarian epithelial malignancy.". Histopathology 38 (2): 87-95. PMID 11207821.
- ↑ GAG 26 Feb 2009.
- ↑ 6.0 6.1 6.2 Urbanczyk K, Skotniczny K, Kucinski J, Friediger J (2005). "Mesothelial inclusion cysts (so-called benign cystic mesothelioma)--a clinicopathological analysis of six cases". Pol J Pathol 56 (2): 81-7. PMID 16092670.
- ↑ Nucci, Marisa R.; Oliva, Esther (2009). Gynecologic Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 384. ISBN 978-0443069208.
- ↑ Asch, E.; Levine, D.; Kim, Y.; Hecht, JL. (Mar 2008). "Histologic, surgical, and imaging correlations of adnexal masses.". J Ultrasound Med 27 (3): 327-42. PMID 18314510.