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→Astroblastoma: are now part of the CNS-PNET family.
Jensflorian (talk | contribs) |
Jensflorian (talk | contribs) (→Astroblastoma: are now part of the CNS-PNET family.) |
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*Large, cystic. Pushing margin towards CNS. | *Large, cystic. Pushing margin towards CNS. | ||
*Vasocentric growth, plump cells with absence of fibrillary pattern. | *Vasocentric growth, plump cells with absence of fibrillary pattern. | ||
*GFAP+ve, Synaptohysin-ve, focally EMA/panCK+ve. MIB-1: 1-18 %. | *GFAP+ve, Synaptohysin-ve, Olig-2-ve, focally EMA/panCK+ve. MIB-1: 1-18 %. | ||
*Molecular profile overlaps with classical [[CNS-PNET]]. | |||
**Gene fusions invoving meningioma gene (MN1)<ref>{{Cite journal | last1 = Sturm | first1 = D. | last2 = Orr | first2 = BA. | last3 = Toprak | first3 = UH. | last4 = Hovestadt | first4 = V. | last5 = Jones | first5 = DT. | last6 = Capper | first6 = D. | last7 = Sill | first7 = M. | last8 = Buchhalter | first8 = I. | last9 = Northcott | first9 = PA. | title = New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs. | journal = Cell | volume = 164 | issue = 5 | pages = 1060-72 | month = Feb | year = 2016 | doi = 10.1016/j.cell.2016.01.015 | PMID = 26919435 }}</ref> | |||
<gallery> | <gallery> | ||