Dysplastic nevus: Difference between revisions

(6 intermediate revisions by the same user not shown)

Line 32:

It is also known as '''atypical nevus''', '''dysplastic melanocytic nevus''', '''Clark nevus''', and '''nevus with architectural disorder'''.

~~The~~ term ''nevus with architectural disorder'' is recommended by the American National Institutes of Health (NIH); however, it is not widely adopted.<ref name=pmid22703907>{{Cite journal | last1 = Elston | first1 = D. | title = Practical advice regarding problematic pigmented lesions. | journal = J Am Acad Dermatol | volume = 67 | issue = 1 | pages = 148-55 | month = Jul | year = 2012 | doi = 10.1016/j.jaad.2012.04.006 | PMID = 22703907 }}</ref> Also, it is the ~~prefered~~ term by only 15% of dermatologists.<ref name=pmid14568850>{{Cite journal | last1 = Fung | first1 = MA. | title = Terminology and management of dysplastic nevi: responses from 145 dermatologists. | journal = Arch Dermatol | volume = 139 | issue = 10 | pages = 1374-5 | month = Oct | year = 2003 | doi = 10.1001/archderm.139.10.1374 | PMID = 14568850 }}</ref>

In 1992, the term ''nevus with architectural disorder'' was recommended by the American National Institutes of Health (NIH);<ref name=pmid1515516>{{Cite journal | title = Diagnosis and treatment of early melanoma. NIH Consensus Development Conference. January 27-29, 1992. | journal = Consens Statement | volume = 10 | issue = 1 | pages = 1-25 | month = | year = | doi = | PMID = 1515516 }}</ref> however, it is not widely adopted.<ref name=pmid22703907>{{Cite journal | last1 = Elston | first1 = D. | title = Practical advice regarding problematic pigmented lesions. | journal = J Am Acad Dermatol | volume = 67 | issue = 1 | pages = 148-55 | month = Jul | year = 2012 | doi = 10.1016/j.jaad.2012.04.006 | PMID = 22703907 }}</ref> Also, based on a 2003 survey, it is the preferred term by only 15% of dermatologists.<ref name=pmid14568850>{{Cite journal | last1 = Fung | first1 = MA. | title = Terminology and management of dysplastic nevi: responses from 145 dermatologists. | journal = Arch Dermatol | volume = 139 | issue = 10 | pages = 1374-5 | month = Oct | year = 2003 | doi = 10.1001/archderm.139.10.1374 | PMID = 14568850 }}</ref>

==General==

Line 62:

**Joining of three or more adjacent rete ridges = suspicious for melanoma.<ref name=pmid15509670/>

*Draping fibrous tissue - "lamellar fibrosis" - collagen deep to epidermis.

*~~Usually~~ moderate ~~nuclear atypia~~ (small nucleoli ~~present~~) - see ''grading'' section.

*Nuclear atypia - often moderate (small nucleoli visible with 20x objective) - see ''grading'' section.

*+/-Junctional component (cells in the epidermis at the DE junction) larger than the intradermal component - ''shoulder phenomenon''.

Line 105:

**A two-tier grading system also exists (''low-grade'' (leave it alone) / ''high-grade'' (cut it out)).

**Some pathologists do not grade dysplastic nevi.

*Normal melanocytes have a nucleus that is ~70% the size of a resting basal keratocyte nucleus.

==Sign out==

Line 129:

Line 130:

- DYSPLASTIC JUNCTIONAL MELANOCYTIC NEVUS WITH MILD NUCLEAR ATYPIA.

- NEAREST MARGIN (LATERAL MARGIN) 1 MM.

</pre>

A comment for lesions with mild cytologic atypia:

<pre>

COMMENT:

Excision of any clinically apparent residual components of the lesion

is suggested.

</pre>

@@ Line 32: / Line 32: @@
 It is also known as '''atypical nevus''', '''dysplastic melanocytic nevus''', '''Clark nevus''', and '''nevus with architectural disorder'''.
-The term ''nevus with architectural disorder'' is recommended by the American National Institutes of Health (NIH); however, it is not widely adopted.<ref name=pmid22703907>{{Cite journal  | last1 = Elston | first1 = D. | title = Practical advice regarding problematic pigmented lesions. | journal = J Am Acad Dermatol | volume = 67 | issue = 1 | pages = 148-55 | month = Jul | year = 2012 | doi = 10.1016/j.jaad.2012.04.006 | PMID = 22703907 }}</ref> Also, it is the prefered term by only 15% of dermatologists.<ref name=pmid14568850>{{Cite journal  | last1 = Fung | first1 = MA. | title = Terminology and management of dysplastic nevi: responses from 145 dermatologists. | journal = Arch Dermatol | volume = 139 | issue = 10 | pages = 1374-5 | month = Oct | year = 2003 | doi = 10.1001/archderm.139.10.1374 | PMID = 14568850 }}</ref>
+In 1992, the term ''nevus with architectural disorder'' was recommended by the American National Institutes of Health (NIH);<ref name=pmid1515516>{{Cite journal  | title = Diagnosis and treatment of early melanoma. NIH Consensus Development Conference. January 27-29, 1992. | journal = Consens Statement | volume = 10 | issue = 1 | pages = 1-25 | month =  | year =  | doi =  | PMID = 1515516 }}</ref> however, it is not widely adopted.<ref name=pmid22703907>{{Cite journal  | last1 = Elston | first1 = D. | title = Practical advice regarding problematic pigmented lesions. | journal = J Am Acad Dermatol | volume = 67 | issue = 1 | pages = 148-55 | month = Jul | year = 2012 | doi = 10.1016/j.jaad.2012.04.006 | PMID = 22703907 }}</ref> Also, based on a 2003 survey, it is the preferred term by only 15% of dermatologists.<ref name=pmid14568850>{{Cite journal  | last1 = Fung | first1 = MA. | title = Terminology and management of dysplastic nevi: responses from 145 dermatologists. | journal = Arch Dermatol | volume = 139 | issue = 10 | pages = 1374-5 | month = Oct | year = 2003 | doi = 10.1001/archderm.139.10.1374 | PMID = 14568850 }}</ref>
 ==General==
@@ Line 62: / Line 62: @@
 **Joining of three or more adjacent rete ridges = suspicious for melanoma.<ref name=pmid15509670/>
 *Draping fibrous tissue - "lamellar fibrosis" - collagen deep to epidermis.
-*Usually moderate nuclear atypia (small nucleoli present) - see ''grading'' section.
+*Nuclear atypia - often moderate (small nucleoli visible with 20x objective) - see ''grading'' section.
 *+/-Junctional component (cells in the epidermis at the DE junction) larger than the intradermal component - ''shoulder phenomenon''.
@@ Line 105: / Line 105: @@
 **A two-tier grading system also exists (''low-grade'' (leave it alone) / ''high-grade'' (cut it out)).
 **Some pathologists do not grade dysplastic nevi.
+*Normal melanocytes have a nucleus that is ~70% the size of a resting basal keratocyte nucleus.
 ==Sign out==
@@ Line 129: / Line 130: @@
 - DYSPLASTIC JUNCTIONAL MELANOCYTIC NEVUS WITH MILD NUCLEAR ATYPIA.
 - NEAREST MARGIN (LATERAL MARGIN) 1 MM.
+</pre>
+A comment for lesions with mild cytologic atypia:
+<pre>
+COMMENT:
+Excision of any clinically apparent residual components of the lesion
+is suggested.
 </pre>

Dysplastic nevus: Difference between revisions

Navigation menu

Search