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| =Metastatic ovarian tumours= | | =Metastatic ovarian tumours= |
| {{Main|Metastases}} | | {{Main|Ovarian metastasis}} |
| ==Generally==
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| * Mostly Muellerian origin (uterus, [[fallopian tube]]) or pelvic [[peritoneum]].
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| ==Extramuellerian metastatic tumours==
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| DDx:
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| * [[Breast]].
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| * [[Gastrointestinal pathology|Gastrointestinal (GI) tract]].
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| ** Pseudomyxoma peritonei, usu. [[appendix|appendiceal]] origin.
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| ** Krukenberg tumour = [[signet ring cell]] cancer with mucin production of GI origin.
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| ===Microscopic===
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| Features:
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| *Predominantly surface involvement and nodular at low power.
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| *[[Signet ring cell]]s (suggestive of GI or breast primary).
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| *[[Lymphovascular invasion]].
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| Image:
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| *[http://commons.wikimedia.org/wiki/File:Adenocarcinoma_of_the_breast_metastatic_to_the_ovary_-_low_mag.jpg Ovarian metastasis - low mag. (WC/Nephron)].
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| ===Mucinous carcinoma - [[GI tract]] metastasis vs. primary ovarian===
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| ====Gross====
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| Features favouring metastatic disease:<ref name=pmid18162780>{{Cite journal | last1 = Yemelyanova | first1 = AV. | last2 = Vang | first2 = R. | last3 = Judson | first3 = K. | last4 = Wu | first4 = LS. | last5 = Ronnett | first5 = BM. | title = Distinction of primary and metastatic mucinous tumors involving the ovary: analysis of size and laterality data by primary site with reevaluation of an algorithm for tumor classification. | journal = Am J Surg Pathol | volume = 32 | issue = 1 | pages = 128-38 | month = Jan | year = 2008 | doi = 10.1097/PAS.0b013e3180690d2d | PMID = 18162780 }}</ref>
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| *Bilaterality -- both ovaries involved.
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| *Small unilateral tumour size -- <10 cm = metastatic.
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| **>13 cm = primary ovarian.
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| ====IHC====
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| Ovarian tumours:
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| *Dipeptidase 1 (DPEP1) +ve.<ref name=pmid21076463>{{Cite journal | last1 = Okamoto | first1 = T. | last2 = Matsumura | first2 = N. | last3 = Mandai | first3 = M. | last4 = Oura | first4 = T. | last5 = Yamanishi | first5 = Y. | last6 = Horiuchi | first6 = A. | last7 = Hamanishi | first7 = J. | last8 = Baba | first8 = T. | last9 = Koshiyama | first9 = M. | title = Distinguishing primary from secondary mucinous ovarian tumors: an algorithm using the novel marker DPEP1. | journal = Mod Pathol | volume = 24 | issue = 2 | pages = 267-76 | month = Feb | year = 2011 | doi = 10.1038/modpathol.2010.204 | PMID = 21076463 }}</ref>
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| *CK7 +ve.
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| =Sex cord stromal tumours= | | =Sex cord stromal tumours= |