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'''Pregnancy luteoma''', also '''luteoma of pregnancy''', is a rare benign [[ovarian tumour]] that arises in [[pregnancy]]. | |||
==General== | |||
*Tumour of pregnancy. | |||
*Benign. | |||
*Regress after pregnancy; thus, conservative management.<ref name=pmid21144088>{{Cite journal | last1 = Masarie | first1 = K. | last2 = Katz | first2 = V. | last3 = Balderston | first3 = K. | title = Pregnancy luteomas: clinical presentations and management strategies. | journal = Obstet Gynecol Surv | volume = 65 | issue = 9 | pages = 575-82 | month = Sep | year = 2010 | doi = 10.1097/OGX.0b013e3181f8c41d | PMID = 21144088 }}</ref> | |||
Clinical: | |||
*Increased serum testosterone.<ref name=pmid15782020>{{Cite journal | last1 = Kao | first1 = HW. | last2 = Wu | first2 = CJ. | last3 = Chung | first3 = KT. | last4 = Wang | first4 = SR. | last5 = Chen | first5 = CY. | title = MR imaging of pregnancy luteoma: a case report and correlation with the clinical features. | journal = Korean J Radiol | volume = 6 | issue = 1 | pages = 44-6 | month = | year = | doi = | PMID = 15782020 }}</ref> | |||
*Increased CA125.<ref name=pmid10546765>{{Cite journal | last1 = Rodriguez | first1 = M. | last2 = Harrison | first2 = TA. | last3 = Nowacki | first3 = MR. | last4 = Saltzman | first4 = AK. | title = Luteoma of pregnancy presenting with massive ascites and markedly elevated CA 125. | journal = Obstet Gynecol | volume = 94 | issue = 5 Pt 2 | pages = 854 | month = Nov | year = 1999 | doi = | PMID = 10546765 }} | |||
</ref><ref name=pmid25785161>{{Cite journal | last1 = Wang | first1 = Y. | last2 = Zhou | first2 = F. | last3 = Qin | first3 = JL. | last4 = Qian | first4 = ZD. | last5 = Huang | first5 = LL. | title = Pregnancy luteoma followed with massive ascites and elevated CA125 after ovulation induction therapy: a case report and review of literatures. | journal = Int J Clin Exp Med | volume = 8 | issue = 1 | pages = 1491-3 | month = | year = 2015 | doi = | PMID = 25785161 }}</ref> | |||
==Gross== | |||
*Solid. | |||
*Yellow. | |||
Images: | |||
*[http://www.flickr.com/photos/78147607@N00/4730745138 Pregnancy luteoma (flickr.com/euthman)]. | |||
*[http://www.flickr.com/photos/euthman/4730754894/in/photostream/ Pregnancy luteoma (flickr.com/euthman)]. | |||
==Microscopic== | |||
Features: | |||
*Sheets of cells. | |||
*Cells with eosinophilic cytoplasm, round nuclei and prominent [[nucleoli]]. | |||
DDx: | |||
*[[Leydig cell tumour]]. | |||
===Images=== | |||
*[http://www.webpathology.com/image.asp?case=522&n=1 Pregnancy luteoma - low mag. (webpathology.com)]. | |||
*[http://www.webpathology.com/image.asp?n=2&Case=522 Pregnancy luteoma - high mag. (webpathology.com)]. | |||
==IHC== | |||
*Inhibin +ve.<ref name=pmid25785161/> | |||
==See also== | |||
*[[Ovary]]. | |||
*[[Ovarian tumours]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Ovarian tumours]] |
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