Ballooning degeneration: Difference between revisions
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[[Image:Ballooning degeneration high mag cropped.jpg|thumb|300px|right|Ballooning degeneration. [[H&E stain]]. (WC)]] | |||
'''Ballooning degeneration''' is a histomorphologic change seen in [[liver pathology]]. It is indicative of [[steatohepatitis]].<ref name=pmid14585234>{{Cite journal | last1 = Liangpunsakul | first1 = S | last2 = Chalasani | first2 = N | title = Treatment of Nonalcoholic Fatty Liver Disease. | journal = Curr Treat Options Gastroenterol | volume = 6 | issue = 6 | pages = 455-463 | month = Dec | year = 2003 | doi = | PMID = 14585234 }}</ref> | '''Ballooning degeneration''' is a histomorphologic change seen in [[liver pathology]]. It is indicative of [[steatohepatitis]].<ref name=pmid14585234>{{Cite journal | last1 = Liangpunsakul | first1 = S | last2 = Chalasani | first2 = N | title = Treatment of Nonalcoholic Fatty Liver Disease. | journal = Curr Treat Options Gastroenterol | volume = 6 | issue = 6 | pages = 455-463 | month = Dec | year = 2003 | doi = | PMID = 14585234 }}</ref> | ||
==General== | ==General== | ||
*A form of apoptosis.<ref name=pmid17355088>{{Cite journal | last1 = Yip | first1 = WW | last2 = Burt | first2 = AD | title = Alcoholic liver disease. | journal = Semin Diagn Pathol | volume = 23 | issue = 3-4 | pages = 149–60 | month = | year = 2006| doi = 10.1053/j.semdp.2006.11.002| pmid = 17355088 }}</ref> | *A form of [[apoptosis]].<ref name=pmid17355088>{{Cite journal | last1 = Yip | first1 = WW | last2 = Burt | first2 = AD | title = Alcoholic liver disease. | journal = Semin Diagn Pathol | volume = 23 | issue = 3-4 | pages = 149–60 | month = | year = 2006| doi = 10.1053/j.semdp.2006.11.002| pmid = 17355088 }}</ref> | ||
*Fatty change without ballooning degeneration is [[steatosis]]. | |||
*Typically seen in the context of [[obesity]] or [[alcohol]]. | |||
==Microscopic== | ==Microscopic== | ||
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DDx: | DDx: | ||
*[[Feathery degeneration]] - has | *[[Feathery degeneration]] - has a similar morphology; however, noticeable (yellow) bile is present. | ||
===Images=== | ===Images=== | ||