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Difference between revisions of "Inflammatory fibroid polyp"
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Inflammatory fibroid polyp (view source)
Revision as of 18:56, 6 December 2015
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| Width = | | Width = | ||
| Caption = Inflammatory fibroid polyp. [[H&E stain]]. | | Caption = Inflammatory fibroid polyp. [[H&E stain]]. | ||
| Micro = proliferating spindle cells - loosely arranged round blood vessels with perivascular hypocellular zones, eosinophils ( | | Micro = proliferating spindle cells - loosely arranged round blood vessels with perivascular hypocellular zones, eosinophils (usually prominent), +/-leiomyoma/schwannoma-like areas - with nuclear palisading | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[inflammatory myofibroblastic tumour]], [[GIST]], [[schwannoma]] | | LMDDx = [[inflammatory myofibroblastic tumour]], [[GIST]], [[hemangiopericytoma]], [[eosinophilic gastritis]], [[schwannoma]] | ||
| Stains = | | Stains = | ||
| IHC = CD34 +ve, vimentin +ve, CD117 -ve, S-100 -ve | | IHC = CD34 +ve, vimentin +ve, CD117 -ve, S-100 -ve | ||
| Line 20: | Line 20: | ||
| Signs = | | Signs = | ||
| Symptoms = | | Symptoms = | ||
| Prevalence = | | Prevalence = uncommon | ||
| Bloodwork = | | Bloodwork = | ||
| Rads = | | Rads = | ||
| Line 28: | Line 28: | ||
| ClinDDx = | | ClinDDx = | ||
}} | }} | ||
'''Inflammatory fibroid polyp''' is an uncommon [[gastrointestinal polyp]]. | '''Inflammatory fibroid polyp''', abbreviated '''IFP''', is an uncommon [[gastrointestinal polyp]]. | ||
==General== | ==General== | ||
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*Through-out GI tract. | *Through-out GI tract. | ||
*Can be thought of as granulation tissue-like.<ref name=Ref_DCHH138/> | *Can be thought of as granulation tissue-like.<ref name=Ref_DCHH138/> | ||
*Uncommon. | |||
==Microscopic== | ==Microscopic== | ||
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*+/-Vascular for fibrous tissue. | *+/-Vascular for fibrous tissue. | ||
*Poorly circumscribed/infiltrates into the lamina propria. | *Poorly circumscribed/infiltrates into the lamina propria. | ||
*+/-Myxoid stroma.<ref name=pmid24764778>{{Cite journal | last1 = Islam | first1 = RS. | last2 = Patel | first2 = NC. | last3 = Lam-Himlin | first3 = D. | last4 = Nguyen | first4 = CC. | title = Gastric polyps: a review of clinical, endoscopic, and histopathologic features and management decisions. | journal = Gastroenterol Hepatol (N Y) | volume = 9 | issue = 10 | pages = 640-51 | month = Oct | year = 2013 | doi = | PMID = 24764778 }}</ref> | |||
DDx: | Notes: | ||
*Concentric = share the same centre.<ref>URL: [http://dictionary.reference.com/browse/concentric http://dictionary.reference.com/browse/concentric]. Accessed on: 29 November 2011.</ref> | |||
DDx:<ref name=pmid22759473>{{Cite journal | last1 = Rossi | first1 = P. | last2 = Montuori | first2 = M. | last3 = Balassone | first3 = V. | last4 = Ricciardi | first4 = E. | last5 = Anemona | first5 = L. | last6 = Manzelli | first6 = A. | last7 = Petrella | first7 = G. | title = Inflammatory fibroid polyp. A case report and review of the literature. | journal = Ann Ital Chir | volume = 83 | issue = 4 | pages = 347-51 | month = | year = | doi = | PMID = 22759473 }}</ref> | |||
*[[Inflammatory myofibroblastic tumour]]. | *[[Inflammatory myofibroblastic tumour]]. | ||
*[[GIST]] - usually sharply demarcated border. | *[[GIST]] - usually sharply demarcated border. | ||
*[[Hemangiopericytoma]]. | |||
*[[Eosinophilic gastritis]]. | |||
* | |||
===Images=== | ===Images=== | ||
| Line 72: | Line 76: | ||
</ref> | </ref> | ||
*S100 -ve. | *S100 -ve. | ||
*Cyclin D1 +ve.<ref name=pmid14707872>{{Cite journal | last1 = Pantanowitz | first1 = L. | last2 = Antonioli | first2 = DA. | last3 = Pinkus | first3 = GS. | last4 = Shahsafaei | first4 = A. | last5 = Odze | first5 = RD. | title = Inflammatory fibroid polyps of the gastrointestinal tract: evidence for a dendritic cell origin. | journal = Am J Surg Pathol | volume = 28 | issue = 1 | pages = 107-14 | month = Jan | year = 2004 | doi = | PMID = 14707872 }}</ref> | |||
==Molecular== | ==Molecular== | ||
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==See also== | ==See also== | ||
*[[Stomach]]. | *[[Stomach]]. | ||
*[[Gastrointestinal tract polyps]]. | |||
==References== | ==References== | ||