Difference between revisions of "Oral fibroma"
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# | '''Oral fibroma''', typically referred to as simply '''fibroma''', is a very common benign lesion in [[oral pathology]]. | ||
It is also known as '''focal fibrous hyperplasia''', '''peripheral fibroma''', ''peripheral ossifying fibroma, ''fibroid epulis'' (old term), and ''fibroepithelial polyp''.<ref name=Ref_Sternberg5_775>{{Ref Sternberg5|775}}</ref><ref>URL: [http://emedicine.medscape.com/article/1080948-overview#aw2aab6b3 http://emedicine.medscape.com/article/1080948-overview#aw2aab6b3]. Accessed on: 20 August 2012.</ref><ref name=Ref_HaNP240>{{Ref HaNP|240}}</ref> | |||
==General== | |||
*Most common oral cavity tumour.<ref name=Ref_HaNP240>{{Ref HaNP|240}}</ref> | |||
*Female predominance (female:male = 2:1), usually 30-50 years old.<ref name=Ref_HaNP240>{{Ref HaNP|240}}</ref> | |||
*Multiple oral fibromas may be seen in [[Cowden disease]].<ref name=pmid16878060>{{Cite journal | last1 = Segura Saint-Gerons | first1 = R. | last2 = Ceballos Salobreña | first2 = A. | last3 = Toro Rojas | first3 = M. | last4 = Gándara Rey | first4 = JM. | title = Oral manifestations of Cowden's disease. Presentation of a clinical case. | journal = Med Oral Patol Oral Cir Bucal | volume = 11 | issue = 5 | pages = E421-4 | month = Aug | year = 2006 | doi = | PMID = 16878060 }}</ref><ref name=pmid20137749>{{Cite journal | last1 = Oliveira | first1 = MA. | last2 = Medina | first2 = JB. | last3 = Xavier | first3 = FC. | last4 = Magalhães | first4 = M. | last5 = Ortega | first5 = KL. | title = Cowden syndrome. | journal = Dermatol Online J | volume = 16 | issue = 1 | pages = 7 | month = | year = 2010 | doi = | PMID = 20137749 | URL = http://dermatology.cdlib.org/1601/case_reports/cowden/ortega.html }}</ref> | |||
*Histologically similar to [[fibrous papule]].<ref name=pmid20421776>{{Cite journal | last1 = Fernandez-Flores | first1 = A. | title = Solitary oral fibromas of the tongue show similar morphologic features to fibrous papule of the face: a study of 31 cases. | journal = Am J Dermatopathol | volume = 32 | issue = 5 | pages = 442-7 | month = Jul | year = 2010 | doi = 10.1097/DAD.0b013e3181c47142 | PMID = 20421776 }}</ref> | |||
==Microscopic== | |||
Features:<ref name=pmid20421776/> | |||
*Fibrous stroma - '''key feature'''. | |||
**"Very pink" at low power. | |||
*+/-Collagen bundles, may be prominent. | |||
*Prominent (dilated) vessels. | |||
*Overlying (squamous) mucosa benign (flat). | |||
**+/-Hyperkeratosis +/-focal ulceration.<ref name=Ref_HaNP240>{{Ref HaNP|240}}</ref> | |||
==Sign out== | |||
<pre> | |||
Lower Buccal Lesion, Left, Excision: | |||
- Fibroma. | |||
- NEGATIVE for malignancy. | |||
</pre> | |||
===Block letters=== | |||
<pre> | |||
TONGUE LESION, BIOPSY: | |||
- FIBROMA. | |||
</pre> | |||
==See also== | |||
*[[Oral pathology]]. | |||
==References== | |||
{{Reflist|1}} | |||
[[Category:Oral pathology]] | |||
Revision as of 13:47, 25 November 2015
Oral fibroma, typically referred to as simply fibroma, is a very common benign lesion in oral pathology.
It is also known as focal fibrous hyperplasia, peripheral fibroma, peripheral ossifying fibroma, fibroid epulis (old term), and fibroepithelial polyp.[1][2][3]
General
- Most common oral cavity tumour.[3]
- Female predominance (female:male = 2:1), usually 30-50 years old.[3]
- Multiple oral fibromas may be seen in Cowden disease.[4][5]
- Histologically similar to fibrous papule.[6]
Microscopic
Features:[6]
- Fibrous stroma - key feature.
- "Very pink" at low power.
- +/-Collagen bundles, may be prominent.
- Prominent (dilated) vessels.
- Overlying (squamous) mucosa benign (flat).
- +/-Hyperkeratosis +/-focal ulceration.[3]
Sign out
Lower Buccal Lesion, Left, Excision: - Fibroma. - NEGATIVE for malignancy.
Block letters
TONGUE LESION, BIOPSY: - FIBROMA.
See also
References
- ↑ Mills, Stacey E; Carter, Darryl; Greenson, Joel K; Reuter, Victor E; Stoler, Mark H (2009). Sternberg's Diagnostic Surgical Pathology (5th ed.). Lippincott Williams & Wilkins. pp. 775. ISBN 978-0781779425.
- ↑ URL: http://emedicine.medscape.com/article/1080948-overview#aw2aab6b3. Accessed on: 20 August 2012.
- ↑ 3.0 3.1 3.2 3.3 Thompson, Lester D. R. (2006). Head and Neck Pathology: A Volume in Foundations in Diagnostic Pathology Series (1st ed.). Churchill Livingstone. pp. 240. ISBN 978-0443069604.
- ↑ Segura Saint-Gerons, R.; Ceballos Salobreña, A.; Toro Rojas, M.; Gándara Rey, JM. (Aug 2006). "Oral manifestations of Cowden's disease. Presentation of a clinical case.". Med Oral Patol Oral Cir Bucal 11 (5): E421-4. PMID 16878060.
- ↑ Oliveira, MA.; Medina, JB.; Xavier, FC.; Magalhães, M.; Ortega, KL. (2010). "Cowden syndrome.". Dermatol Online J 16 (1): 7. PMID 20137749.
- ↑ 6.0 6.1 Fernandez-Flores, A. (Jul 2010). "Solitary oral fibromas of the tongue show similar morphologic features to fibrous papule of the face: a study of 31 cases.". Am J Dermatopathol 32 (5): 442-7. doi:10.1097/DAD.0b013e3181c47142. PMID 20421776.