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Difference between revisions of "Heart transplant pathology"
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Heart transplant pathology (view source)
Revision as of 00:39, 14 February 2011
, 00:39, 14 February 2011→Quilty: revised.... not subclassified any more
(more +PTLD) |
(→Quilty: revised.... not subclassified any more) |
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Image: [http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig6 Biopsy site (pathconsultddx.com)]. | Image: [http://www.pathconsultddx.com/pathCon/largeImage?pii=S1559-8675%2806%2970592-7&figureId=fig6 Biopsy site (pathconsultddx.com)]. | ||
==Quilty== | ==Quilty effect== | ||
*[[AKA]] ''endocardial lymphocytic infiltrate''.<ref name=pmid17683180>{{cite journal |author=Tan CD, Baldwin WM, Rodriguez ER |title=Update on cardiac transplantation pathology |journal=Arch. Pathol. Lab. Med. |volume=131 |issue=8 |pages=1169–91 |year=2007 |month=August |pmid=17683180 |doi= |url=}}</ref> | |||
===General=== | ===General=== | ||
*Can be confused for rejection. | *Can be confused for rejection. | ||
*Benign behaviour. | *Benign behaviour. | ||
Trivia: | |||
*The name ''Quilty'' comes from the patient in which this was first recognized. | |||
===Microscopic=== | ===Microscopic=== | ||
Features: | Features: | ||
*B-lymphocytes (in clusters). | *B-lymphocytes (in clusters). | ||
* | **'''Not''' associated with blood vessels. | ||
**Quilty A: Endocardial/subendocardial. | *Usually endocardial, i.e. associated with the endocardium ("endothelium of the heart"). | ||
**Quilty B: Endocardial/subendocardial + myocardium. | |||
****+/-Myocyte damage.<ref name=pmid9192483>{{cite journal |author=Winters GL |title=The challenge of endomyocardial biopsy interpretation in assessing cardiac allograft rejection |journal=Curr. Opin. Cardiol. |volume=12 |issue=2 |pages=146–52 |year=1997 |month=March |pmid=9192483 |doi= |url=}}</ref> | Notes: | ||
*No longer subclassified.<ref name=pmid17683180/> | |||
**Traditional classification (by location): | |||
***Quilty A: Endocardial/subendocardial. | |||
***Quilty B: Endocardial/subendocardial + myocardium. | |||
*****+/-Myocyte damage.<ref name=pmid9192483>{{cite journal |author=Winters GL |title=The challenge of endomyocardial biopsy interpretation in assessing cardiac allograft rejection |journal=Curr. Opin. Cardiol. |volume=12 |issue=2 |pages=146–52 |year=1997 |month=March |pmid=9192483 |doi= |url=}}</ref> | |||
Images: | Images: | ||