Kimura disease: Difference between revisions
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{{ Infobox diagnosis | {{ Infobox diagnosis | ||
| Name = {{PAGENAME}} | | Name = {{PAGENAME}} | ||
| Image = Kimura_disease_-_very_high_mag.jpg | | Image = Kimura_disease_-_very_high_mag.jpg | ||
| Width = | | Width = | ||
| Caption = Kimura disease. [[H&E stain]]. | | Caption = Kimura disease. [[H&E stain]]. | ||
| Micro = eosinophils and thick walled [[blood vessel]]s with | | Micro = eosinophils and thick walled [[blood vessel]]s with [[hobnail]]ed endothelial cells | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[angiolymphoid hyperplasia with eosinophilia]], [[drug reaction]], infection (parasitic), [[lymphoma]], [[LCH]] | | LMDDx = [[angiolymphoid hyperplasia with eosinophilia]], [[drug reaction]], infection (parasitic), [[lymphoma]], [[LCH]] | ||
| Line 15: | Line 15: | ||
| Grossing = | | Grossing = | ||
| Site = [[lymph node]], head and neck | | Site = [[lymph node]], head and neck | ||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | | Signs = | ||
| Symptoms = | | Symptoms = | ||
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Features:<ref name=Ref_ILNP190>{{Ref ILNP|190}}</ref> | Features:<ref name=Ref_ILNP190>{{Ref ILNP|190}}</ref> | ||
*Angiolymphoid proliferation. | *Angiolymphoid proliferation. | ||
**Thick walled blood vessels with (plump) hobnail endothelial cells.<ref>URL: [http://emedicine.medscape.com/article/1098777-diagnosis http://emedicine.medscape.com/article/1098777-diagnosis]. Accessed on: 8 August 2010.</ref> | **Thick walled blood vessels with (plump) [[hobnail]] endothelial cells.<ref>URL: [http://emedicine.medscape.com/article/1098777-diagnosis http://emedicine.medscape.com/article/1098777-diagnosis]. Accessed on: 8 August 2010.</ref> | ||
*Eosinophils - abundant - '''key feature'''. | *Eosinophils - abundant - '''key feature'''. | ||
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Image:Kimura_disease_-_intermed_mag.jpg | Kimura disease - intermed. mag. (WC) | Image:Kimura_disease_-_intermed_mag.jpg | Kimura disease - intermed. mag. (WC) | ||
</gallery> | </gallery> | ||
==IHC== | ==IHC== | ||
*Used to rule-out a clonal population, i.e. [[lymphoma]]. | *Used to rule-out a clonal population, i.e. [[lymphoma]]. | ||