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Image: Proliferative fibrocystic changes -- very high mag.jpg|PFCC - very high mag. | Image: Proliferative fibrocystic changes -- very high mag.jpg|PFCC - very high mag. | ||
</gallery> | </gallery> | ||
==IHC== | |||
Features:<ref name=pmid19675450>{{Cite journal | last1 = Grin | first1 = A. | last2 = O'Malley | first2 = FP. | last3 = Mulligan | first3 = AM. | title = Cytokeratin 5 and estrogen receptor immunohistochemistry as a useful adjunct in identifying atypical papillary lesions on breast needle core biopsy. | journal = Am J Surg Pathol | volume = 33 | issue = 11 | pages = 1615-23 | month = Nov | year = 2009 | doi = 10.1097/PAS.0b013e3181aec446 | PMID = 19675450 }}</ref> | |||
*ER "low". | |||
*CK5 "high". | |||
Where: | |||
*ER "high" = diffuse strong staining in >90% of cells. | |||
*CK5 "high" = mosaic pattern of staining in >20% of cells | |||
*CK5 "low" = absent or staining in <20% of cells. | |||
Note: | |||
*ADH/DCIS: | |||
**ER "high" | |||
**CK5 "low". | |||
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