Difference between revisions of "Branchial cleft cyst"
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'''Branchial cleft cyst''', also '''branchial cleft remnant''', is a benign congenital lesion of the [[head and neck pathology|head and neck]]. | |||
==General== | |||
*Benign congenital thingy in the lateral neck.<ref>URL: [http://www.childrenshospital.org/az/Site663/mainpageS663P0.html http://www.childrenshospital.org/az/Site663/mainpageS663P0.html]. Accessed on: 15 March 2011.</ref> | |||
*Most common cystic neck lesion in young adults.<ref name=pmid19593684>{{Cite journal | last1 = Pietarinen-Runtti | first1 = P. | last2 = Apajalahti | first2 = S. | last3 = Robinson | first3 = S. | last4 = Passador-Santos | first4 = F. | last5 = Leivo | first5 = I. | last6 = Mäkitie | first6 = AA. | title = Cystic neck lesions: clinical, radiological and differential diagnostic considerations. | journal = Acta Otolaryngol | volume = 130 | issue = 2 | pages = 300-4 | month = Feb | year = 2010 | doi = 10.3109/00016480903127450 | PMID = 19593684 }}</ref> | |||
*Treatment: excision. | |||
==Gross== | |||
*Lateral neck mass. | |||
Image - clinical: | |||
*[http://medical-dictionary.thefreedictionary.com/_/viewer.aspx?path=mosby&name=500051-fx23.jpg Branchial cleft cyst (thefreedictionary.com)]. | |||
==Microscopic== | |||
Features: | |||
*Cystic space lined by squamous epithelium - usually. | |||
**+/-Inflammation. | |||
*Connective tissue: | |||
**+/-Adipose tissue. | |||
**+/-Cartilage. | |||
**+/-Bone. | |||
**+/-Muscle. | |||
DDx: | |||
*Cystic [[squamous cell carcinoma]] - may be deceptively benign appearing.<ref name=pmid19593684>{{Cite journal | last1 = Pietarinen-Runtti | first1 = P. | last2 = Apajalahti | first2 = S. | last3 = Robinson | first3 = S. | last4 = Passador-Santos | first4 = F. | last5 = Leivo | first5 = I. | last6 = Mäkitie | first6 = AA. | title = Cystic neck lesions: clinical, radiological and differential diagnostic considerations. | journal = Acta Otolaryngol | volume = 130 | issue = 2 | pages = 300-4 | month = Feb | year = 2010 | doi = 10.3109/00016480903127450 | PMID = 19593684 }}</ref> | |||
*[[Papillary thyroid carcinoma]] (PTC) arising in a brachial cleft cyst<ref name=pmid20187788>{{Cite journal | last1 = Park | first1 = J. | last2 = Kwon | first2 = SY. | last3 = Kim | first3 = NH. | last4 = Baik | first4 = SH. | last5 = Choi | first5 = DS. | title = Papillary thyroid carcinoma arising in a branchial cleft cyst. | journal = Thyroid | volume = 20 | issue = 3 | pages = 347-9 | month = Mar | year = 2010 | doi = 10.1089/thy.2009.0124 | PMID = 20187788 }}</ref> - uncommon, looks like PTC in the thyroid. | |||
*[[Epidermal inclusion cyst]]. | |||
===Images=== | |||
*[http://www.flickr.com/photos/jian-hua_qiao_md/8599213842/in/photostream/ BCC (flickr.com/Qiao)]. | |||
*[http://www.flickr.com/photos/jian-hua_qiao_md/8599214250/in/photostream/ BCC (flickr.com/Qiao)]. | |||
==IHC== | |||
*p16 -ve. | |||
**May be done to exclude a [[HPV-associated head and neck squamous cell carcinoma]]. | |||
*Ki-67 low. | |||
==Sign out== | |||
<pre> | |||
Right Neck Mass, Fine Needle Aspiration (FNA): | |||
- Benign squamous cells and debris admixed in a background of inflammatory cells. | |||
- Moderately cellular specimen. | |||
Comment: | |||
The differential diagnosis includes branchial cleft cyst and epidermal inclusion | |||
cyst. Clinical correlation is required. | |||
</pre> | |||
==See also== | |||
*[[Head and neck pathology]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Head and neck pathology]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
Latest revision as of 14:44, 16 October 2015
Branchial cleft cyst, also branchial cleft remnant, is a benign congenital lesion of the head and neck.
General
- Benign congenital thingy in the lateral neck.[1]
- Most common cystic neck lesion in young adults.[2]
- Treatment: excision.
Gross
- Lateral neck mass.
Image - clinical:
Microscopic
Features:
- Cystic space lined by squamous epithelium - usually.
- +/-Inflammation.
- Connective tissue:
- +/-Adipose tissue.
- +/-Cartilage.
- +/-Bone.
- +/-Muscle.
DDx:
- Cystic squamous cell carcinoma - may be deceptively benign appearing.[2]
- Papillary thyroid carcinoma (PTC) arising in a brachial cleft cyst[3] - uncommon, looks like PTC in the thyroid.
- Epidermal inclusion cyst.
Images
IHC
- p16 -ve.
- May be done to exclude a HPV-associated head and neck squamous cell carcinoma.
- Ki-67 low.
Sign out
Right Neck Mass, Fine Needle Aspiration (FNA): - Benign squamous cells and debris admixed in a background of inflammatory cells. - Moderately cellular specimen. Comment: The differential diagnosis includes branchial cleft cyst and epidermal inclusion cyst. Clinical correlation is required.
See also
References
- ↑ URL: http://www.childrenshospital.org/az/Site663/mainpageS663P0.html. Accessed on: 15 March 2011.
- ↑ 2.0 2.1 Pietarinen-Runtti, P.; Apajalahti, S.; Robinson, S.; Passador-Santos, F.; Leivo, I.; Mäkitie, AA. (Feb 2010). "Cystic neck lesions: clinical, radiological and differential diagnostic considerations.". Acta Otolaryngol 130 (2): 300-4. doi:10.3109/00016480903127450. PMID 19593684.
- ↑ Park, J.; Kwon, SY.; Kim, NH.; Baik, SH.; Choi, DS. (Mar 2010). "Papillary thyroid carcinoma arising in a branchial cleft cyst.". Thyroid 20 (3): 347-9. doi:10.1089/thy.2009.0124. PMID 20187788.