Branchial cleft cyst: Difference between revisions

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~~#redirect~~ [[~~Head~~ and neck pathology#Branchial cleft cyst]]

'''Branchial cleft cyst''', also '''branchial cleft remnant''', is a benign congenital lesion of the [[head and neck pathology|head and neck]].

==General==

*Benign congenital thingy in the lateral neck.<ref>URL: [http://www.childrenshospital.org/az/Site663/mainpageS663P0.html http://www.childrenshospital.org/az/Site663/mainpageS663P0.html]. Accessed on: 15 March 2011.</ref>

*Most common cystic neck lesion in young adults.<ref name=pmid19593684>{{Cite journal | last1 = Pietarinen-Runtti | first1 = P. | last2 = Apajalahti | first2 = S. | last3 = Robinson | first3 = S. | last4 = Passador-Santos | first4 = F. | last5 = Leivo | first5 = I. | last6 = Mäkitie | first6 = AA. | title = Cystic neck lesions: clinical, radiological and differential diagnostic considerations. | journal = Acta Otolaryngol | volume = 130 | issue = 2 | pages = 300-4 | month = Feb | year = 2010 | doi = 10.3109/00016480903127450 | PMID = 19593684 }}</ref>

*Treatment: excision.

==Gross==

*Lateral neck mass.

Image - clinical:

*[http://medical-dictionary.thefreedictionary.com/_/viewer.aspx?path=mosby&name=500051-fx23.jpg Branchial cleft cyst (thefreedictionary.com)].

==Microscopic==

Features:

*Cystic space lined by squamous epithelium - usually.

**+/-Inflammation.

*Connective tissue:

**+/-Adipose tissue.

**+/-Cartilage.

**+/-Bone.

**+/-Muscle.

DDx:

*Cystic [[squamous cell carcinoma]] - may be deceptively benign appearing.<ref name=pmid19593684>{{Cite journal | last1 = Pietarinen-Runtti | first1 = P. | last2 = Apajalahti | first2 = S. | last3 = Robinson | first3 = S. | last4 = Passador-Santos | first4 = F. | last5 = Leivo | first5 = I. | last6 = Mäkitie | first6 = AA. | title = Cystic neck lesions: clinical, radiological and differential diagnostic considerations. | journal = Acta Otolaryngol | volume = 130 | issue = 2 | pages = 300-4 | month = Feb | year = 2010 | doi = 10.3109/00016480903127450 | PMID = 19593684 }}</ref>

*[[Papillary thyroid carcinoma]] (PTC) arising in a brachial cleft cyst<ref name=pmid20187788>{{Cite journal | last1 = Park | first1 = J. | last2 = Kwon | first2 = SY. | last3 = Kim | first3 = NH. | last4 = Baik | first4 = SH. | last5 = Choi | first5 = DS. | title = Papillary thyroid carcinoma arising in a branchial cleft cyst. | journal = Thyroid | volume = 20 | issue = 3 | pages = 347-9 | month = Mar | year = 2010 | doi = 10.1089/thy.2009.0124 | PMID = 20187788 }}</ref> - uncommon, looks like PTC in the thyroid.

*[[Epidermal inclusion cyst]].

===Images===

*[http://www.flickr.com/photos/jian-hua_qiao_md/8599213842/in/photostream/ BCC (flickr.com/Qiao)].

*[http://www.flickr.com/photos/jian-hua_qiao_md/8599214250/in/photostream/ BCC (flickr.com/Qiao)].

==IHC==

*p16 -ve.

**May be done to exclude a [[HPV-associated head and neck squamous cell carcinoma]].

*Ki-67 low.

==Sign out==

<pre>

Right Neck Mass, Fine Needle Aspiration (FNA):

- Benign squamous cells and debris admixed in a background of inflammatory cells.

- Moderately cellular specimen.

Comment:

The differential diagnosis includes branchial cleft cyst and epidermal inclusion

cyst. Clinical correlation is required.

</pre>

==See also==

*[[Head and neck pathology]].

==References==

[[Category:Head and neck pathology]]

[[Category:Diagnosis]]

@@ Line 1: / Line 1: @@
-#redirect [[Head and neck pathology#Branchial cleft cyst]]
+'''Branchial cleft cyst''', also '''branchial cleft remnant''', is a benign congenital lesion of the [[head and neck pathology|head and neck]].
+==General==
+*Benign congenital thingy in the lateral neck.<ref>URL: [http://www.childrenshospital.org/az/Site663/mainpageS663P0.html http://www.childrenshospital.org/az/Site663/mainpageS663P0.html]. Accessed on: 15 March 2011.</ref>
+*Most common cystic neck lesion in young adults.<ref name=pmid19593684>{{Cite journal  | last1 = Pietarinen-Runtti | first1 = P. | last2 = Apajalahti | first2 = S. | last3 = Robinson | first3 = S. | last4 = Passador-Santos | first4 = F. | last5 = Leivo | first5 = I. | last6 = Mäkitie | first6 = AA. | title = Cystic neck lesions: clinical, radiological and differential diagnostic considerations. | journal = Acta Otolaryngol | volume = 130 | issue = 2 | pages = 300-4 | month = Feb | year = 2010 | doi = 10.3109/00016480903127450 | PMID = 19593684 }}</ref>
+*Treatment: excision.
+==Gross==
+*Lateral neck mass.
+Image - clinical:
+*[http://medical-dictionary.thefreedictionary.com/_/viewer.aspx?path=mosby&name=500051-fx23.jpg Branchial cleft cyst (thefreedictionary.com)].
+==Microscopic==
+Features:
+*Cystic space lined by squamous epithelium - usually.
+**+/-Inflammation.
+*Connective tissue:
+**+/-Adipose tissue.
+**+/-Cartilage.
+**+/-Bone.
+**+/-Muscle.
+DDx:
+*Cystic [[squamous cell carcinoma]] - may be deceptively benign appearing.<ref name=pmid19593684>{{Cite journal  | last1 = Pietarinen-Runtti | first1 = P. | last2 = Apajalahti | first2 = S. | last3 = Robinson | first3 = S. | last4 = Passador-Santos | first4 = F. | last5 = Leivo | first5 = I. | last6 = Mäkitie | first6 = AA. | title = Cystic neck lesions: clinical, radiological and differential diagnostic considerations. | journal = Acta Otolaryngol | volume = 130 | issue = 2 | pages = 300-4 | month = Feb | year = 2010 | doi = 10.3109/00016480903127450 | PMID = 19593684 }}</ref>
+*[[Papillary thyroid carcinoma]] (PTC) arising in a brachial cleft cyst<ref name=pmid20187788>{{Cite journal  | last1 = Park | first1 = J. | last2 = Kwon | first2 = SY. | last3 = Kim | first3 = NH. | last4 = Baik | first4 = SH. | last5 = Choi | first5 = DS. | title = Papillary thyroid carcinoma arising in a branchial cleft cyst. | journal = Thyroid | volume = 20 | issue = 3 | pages = 347-9 | month = Mar | year = 2010 | doi = 10.1089/thy.2009.0124 | PMID = 20187788 }}</ref> - uncommon, looks like PTC in the thyroid.
+*[[Epidermal inclusion cyst]].
+===Images===
+*[http://www.flickr.com/photos/jian-hua_qiao_md/8599213842/in/photostream/ BCC (flickr.com/Qiao)].
+*[http://www.flickr.com/photos/jian-hua_qiao_md/8599214250/in/photostream/ BCC (flickr.com/Qiao)].
+==IHC==
+*p16 -ve.
+**May be done to exclude a [[HPV-associated head and neck squamous cell carcinoma]].
+*Ki-67 low.
+==Sign out==
+<pre>
+Right Neck Mass, Fine Needle Aspiration (FNA):
+- Benign squamous cells and debris admixed in a background of inflammatory cells.
+- Moderately cellular specimen.
+Comment:
+The differential diagnosis includes branchial cleft cyst and epidermal inclusion
+cyst. Clinical correlation is required.
+</pre>
+==See also==
+*[[Head and neck pathology]].
+==References==
+{{Reflist|2}}
+[[Category:Head and neck pathology]]
+[[Category:Diagnosis]]

Branchial cleft cyst: Difference between revisions

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