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Difference between revisions of "Case 116"
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(Created page with "===Provided clinical history=== 45 year old woman, with intractable uterine bleeding unresponsive to hormone therapy. Mass lesion in the myometrium ===Site=== Uterus- myomet...") |
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[[Image: Leiomyoma with changes secondary to tranexamic acid treatment low magnification.jpg |500px|link=|center|]] | [[Image: Leiomyoma with changes secondary to tranexamic acid treatment low magnification.jpg |500px|link=|center|]] | ||
<center>Low magnification. [[H&E stain]].</center> | <center>Low magnification. [[H&E stain]].</center> | ||
{{hidden|High magnification|[[Image: Leiomyoma with changes secondary to tranexamic acid treatment high magnification.jpg |500px|link=|center|]] | {{hidden|High magnification|[[Image: Leiomyoma with changes secondary to tranexamic acid treatment high magnification.jpg |500px|link=|center|]] | ||
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===Differential diagnosis=== | ===Differential diagnosis=== | ||
{{hidden|Differential diagnosis|<center>Smooth muscle | {{hidden|Differential diagnosis|<center>[[Smooth muscle tumour of uncertain malignant potential]] (STUMP), [[uterine leiomyosarcoma]]</center>}} | ||
===Additional tests=== | ===Additional tests=== | ||
====More history==== | ====More history==== | ||
{{hidden|More history|<center>Patient had received lysteda for control of bleeding </center>}} | {{hidden|More history|<center>Patient had received lysteda for control of bleeding.</center>}} | ||
====Ask a colleague==== | ====Ask a colleague==== | ||
{{hidden|Ask a colleague|<center> | {{hidden|Ask a colleague|<center>Did you check the history? I wonder whether this could be drug effect.</center>}} | ||
====Stains==== | ====Stains==== | ||
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===Diagnosis=== | ===Diagnosis=== | ||
{{hidden|Diagnosis|<center>LEIOMYOMA WITH TRANEXAMIC ACID ASSOCIATED MICROINFARCTION | {{hidden|Diagnosis|<center>[[uterine leiomyoma|LEIOMYOMA]] WITH TRANEXAMIC ACID ASSOCIATED MICROINFARCTION</center><br> | ||
This smooth muscle tumor depicts no atypia. When in this situation it is prudent to request detailed [[clinical history]]. Clinicians often do not inform of all agents given to patients to control uterine bleeding.<ref name=pmid17667546>{{Cite journal | last1 = Ip | first1 = PP. | last2 = Lam | first2 = KW. | last3 = Cheung | first3 = CL. | last4 = Yeung | first4 = MC. | last5 = Pun | first5 = TC. | last6 = Chan | first6 = QK. | last7 = Cheung | first7 = AN. | title = Tranexamic acid-associated necrosis and intralesional thrombosis of uterine leiomyomas: a clinicopathologic study of 147 cases emphasizing the importance of drug-induced necrosis and early infarcts in leiomyomas. | journal = Am J Surg Pathol | volume = 31 | issue = 8 | pages = 1215-24 | month = Aug | year = 2007 | doi = 10.1097/PAS.0b013e318032125e | PMID = 17667546 }}</ref> | |||
===References=== | |||
{{Reflist|1}} | |||
}} | |||
<br> | <br> | ||
===Other cases=== | ===Other cases=== | ||
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[[Category:Cases]] | [[Category:Cases]] | ||
[[Category:Cases in gynecologic pathology]] | [[Category:Cases in gynecologic pathology]] | ||
- | [[Category:Cases in gynecologic pathology - fellow and expert]] | ||
[[Category:Cases difficulty 7]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level --> | [[Category:Cases difficulty 7]] <!-- difficulty 1-7 -- should roughly correspond to the PGY level --> | ||