48,836
edits
(→Renal cell carcinoma staging: more) |
|||
Line 415: | Line 415: | ||
**Now only ''N1'' - was changed in 2009.<ref name=pmid21927698>{{Cite journal | last1 = Lee | first1 = C. | last2 = You | first2 = D. | last3 = Park | first3 = J. | last4 = Jeong | first4 = IG. | last5 = Song | first5 = C. | last6 = Hong | first6 = JH. | last7 = Ahn | first7 = H. | last8 = Kim | first8 = CS. | title = Validation of the 2009 TNM Classification for Renal Cell Carcinoma: Comparison with the 2002 TNM Classification by Concordance Index. | journal = Korean J Urol | volume = 52 | issue = 8 | pages = 524-30 | month = Aug | year = 2011 | doi = 10.4111/kju.2011.52.8.524 | PMID = 21927698 }}</ref> | **Now only ''N1'' - was changed in 2009.<ref name=pmid21927698>{{Cite journal | last1 = Lee | first1 = C. | last2 = You | first2 = D. | last3 = Park | first3 = J. | last4 = Jeong | first4 = IG. | last5 = Song | first5 = C. | last6 = Hong | first6 = JH. | last7 = Ahn | first7 = H. | last8 = Kim | first8 = CS. | title = Validation of the 2009 TNM Classification for Renal Cell Carcinoma: Comparison with the 2002 TNM Classification by Concordance Index. | journal = Korean J Urol | volume = 52 | issue = 8 | pages = 524-30 | month = Aug | year = 2011 | doi = 10.4111/kju.2011.52.8.524 | PMID = 21927698 }}</ref> | ||
***There is data to suggest N1 and N2 behave differently;<ref name=pmid16469567>{{Cite journal | last1 = Canfield | first1 = SE. | last2 = Kamat | first2 = AM. | last3 = Sánchez-Ortiz | first3 = RF. | last4 = Detry | first4 = M. | last5 = Swanson | first5 = DA. | last6 = Wood | first6 = CG. | title = Renal cell carcinoma with nodal metastases in the absence of distant metastatic disease (clinical stage TxN1-2M0): the impact of aggressive surgical resection on patient outcome. | journal = J Urol | volume = 175 | issue = 3 Pt 1 | pages = 864-9 | month = Mar | year = 2006 | doi = 10.1016/S0022-5347(05)00334-4 | PMID = 16469567 }}</ref> however, it is disputed.<ref name=pmid17070225>{{Cite journal | last1 = Dimashkieh | first1 = HH. | last2 = Lohse | first2 = CM. | last3 = Blute | first3 = ML. | last4 = Kwon | first4 = ED. | last5 = Leibovich | first5 = BC. | last6 = Cheville | first6 = JC. | title = Extranodal extension in regional lymph nodes is associated with outcome in patients with renal cell carcinoma. | journal = J Urol | volume = 176 | issue = 5 | pages = 1978-82; discussion 1982-3 | month = Nov | year = 2006 | doi = 10.1016/j.juro.2006.07.026 | PMID = 17070225 }}</ref><ref name=pmid19955666>{{Cite journal | last1 = Lam | first1 = JS. | last2 = Klatte | first2 = T. | last3 = Breda | first3 = A. | title = Staging of renal cell carcinoma: Current concepts. | journal = Indian J Urol | volume = 25 | issue = 4 | pages = 446-54 | month = | year = | doi = 10.4103/0970-1591.57906 | PMID = 19955666 }}</ref> | ***There is data to suggest N1 and N2 behave differently;<ref name=pmid16469567>{{Cite journal | last1 = Canfield | first1 = SE. | last2 = Kamat | first2 = AM. | last3 = Sánchez-Ortiz | first3 = RF. | last4 = Detry | first4 = M. | last5 = Swanson | first5 = DA. | last6 = Wood | first6 = CG. | title = Renal cell carcinoma with nodal metastases in the absence of distant metastatic disease (clinical stage TxN1-2M0): the impact of aggressive surgical resection on patient outcome. | journal = J Urol | volume = 175 | issue = 3 Pt 1 | pages = 864-9 | month = Mar | year = 2006 | doi = 10.1016/S0022-5347(05)00334-4 | PMID = 16469567 }}</ref> however, it is disputed.<ref name=pmid17070225>{{Cite journal | last1 = Dimashkieh | first1 = HH. | last2 = Lohse | first2 = CM. | last3 = Blute | first3 = ML. | last4 = Kwon | first4 = ED. | last5 = Leibovich | first5 = BC. | last6 = Cheville | first6 = JC. | title = Extranodal extension in regional lymph nodes is associated with outcome in patients with renal cell carcinoma. | journal = J Urol | volume = 176 | issue = 5 | pages = 1978-82; discussion 1982-3 | month = Nov | year = 2006 | doi = 10.1016/j.juro.2006.07.026 | PMID = 17070225 }}</ref><ref name=pmid19955666>{{Cite journal | last1 = Lam | first1 = JS. | last2 = Klatte | first2 = T. | last3 = Breda | first3 = A. | title = Staging of renal cell carcinoma: Current concepts. | journal = Indian J Urol | volume = 25 | issue = 4 | pages = 446-54 | month = | year = | doi = 10.4103/0970-1591.57906 | PMID = 19955666 }}</ref> | ||
===Renal sinus invasion=== | |||
Renal sinus invasion is when tumour is found in any of the following:<ref name=pmid24025521>{{Cite journal | last1 = Trpkov | first1 = K. | last2 = Grignon | first2 = DJ. | last3 = Bonsib | first3 = SM. | last4 = Amin | first4 = MB. | last5 = Billis | first5 = A. | last6 = Lopez-Beltran | first6 = A. | last7 = Samaratunga | first7 = H. | last8 = Tamboli | first8 = P. | last9 = Delahunt | first9 = B. | title = Handling and staging of renal cell carcinoma: the International Society of Urological Pathology Consensus (ISUP) conference recommendations. | journal = Am J Surg Pathol | volume = 37 | issue = 10 | pages = 1505-17 | month = Oct | year = 2013 | doi = 10.1097/PAS.0b013e31829a85d0 | PMID = 24025521 }}</ref> | |||
*An endothelial lined space of the renal sinus. | |||
*Sinus fat of the renal sinus. | |||
*Loose connective tissue of the renal sinus. | |||
==Clear cell renal cell carcinoma== | ==Clear cell renal cell carcinoma== |
edits