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Difference between revisions of "Medical lung diseases"
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+asthma
(→Diffuse alveolar damage: more, image lnk) |
(+asthma) |
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*+/-Clusters of bacteria - small dots or rods. | *+/-Clusters of bacteria - small dots or rods. | ||
==Asthma== | |||
===General=== | |||
*The bread and butter of respirology. | |||
*Associated with atopy. | |||
*Mast cells thought to play an important role. | |||
===Microscopic=== | |||
Features:<ref>Klatt. AOP P.108.</ref> | |||
*Edema. | |||
*Mucous. | |||
*+/-Smooth muscle hypertrophy. | |||
*+/-Inflammation - especially with eosinophils. | |||
*+/-Charcot-Leyden crystals (formed from eosinophilic granules). | |||
**Sharp edge, diamond shaped, intense pink. | |||
Images: | |||
*[http://www.udel.edu/medtech/dlehman/medt372/Ch-lyd.html Charcot-Leyden crystals (udel.edu)]. | |||
*[http://www.som.tulane.edu/classware/pathology/medical_pathology/New_for_98/Lung_Review/Lung-26.html Charcot-Leyden crystals (tulane.edu)]. | |||
Notes: | |||
*Leyden in ''Charcot-Leyden'' is also seen written as ''Leiden''. | |||
==Idiopathic interstitial pneumonia== | ==Idiopathic interstitial pneumonia== | ||
| Line 59: | Line 80: | ||
Notes: | Notes: | ||
*''Usual interstitial pneumonia'' is the most common type of ILD.<ref name="pmid16738196">{{cite journal |author=Visscher DW, Myers JL |title=Histologic spectrum of idiopathic interstitial pneumonias |journal=Proc Am Thorac Soc |volume=3 |issue=4 |pages=322-9 |year=2006 |month=June |pmid=16738196 |doi=10.1513/pats.200602-019TK |url=http://pats.atsjournals.org/cgi/pmidlookup?view=long&pmid=16738196}}</ref> | *''Usual interstitial pneumonia'' is the most common type of ILD.<ref name="pmid16738196">{{cite journal |author=Visscher DW, Myers JL |title=Histologic spectrum of idiopathic interstitial pneumonias |journal=Proc Am Thorac Soc |volume=3 |issue=4 |pages=322-9 |year=2006 |month=June |pmid=16738196 |doi=10.1513/pats.200602-019TK |url=http://pats.atsjournals.org/cgi/pmidlookup?view=long&pmid=16738196}}</ref> | ||
==Fibrosis== | ==Fibrosis== | ||
| Line 124: | Line 123: | ||
=Disease with fibrosis= | =Disease with fibrosis= | ||
There are many of 'em. | |||
==Diffuse alveolar damage== | |||
===General=== | |||
*Abbreviated ''DAD''. | |||
DAD is the histologic correlate of: | |||
*Adult respiratory distress syndrome (ARDS). | |||
*Acute interstitial pneumonia (AIP). | |||
*Transfusion related acute lung injury (TRALI). | |||
===Microscopic=== | |||
Features:<ref>Klatt. AOP P.103.</ref> | |||
*Early: | |||
**Hyaline membrane: debris (pink crap) lines the alveolar spaces. | |||
*Intermediate: | |||
**Macrophage proliferation. | |||
*Late: | |||
**Interstitial inflammation. | |||
**Fibrosis. | |||
Image: [http://commons.wikimedia.org/wiki/File:ARDS.jpg Diffuse alveolar damage (WC)]. | |||
==Usual interstitial pneumonia== | ==Usual interstitial pneumonia== | ||