Difference between revisions of "Mucinous fibroplasia"
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[[Image:Mucinous fibroplasia -- very high mag.jpg|thumb|300px|[[Micrograph]] showing mucinous fibroplasia. [[H&E stain]]. (WC)]] | |||
'''Mucinous fibroplasia''', also '''collagenous micronodules''', is a finding seen in the [[prostate gland]] that is considered pathognomonic for [[prostate carcinoma]] by many genitourinary pathologists.<ref name=pmid16613324>{{Cite journal | last1 = Egevad | first1 = L. | last2 = Allsbrook | first2 = WC. | last3 = Epstein | first3 = JI. | title = Current practice of diagnosis and reporting of prostate cancer on needle biopsy among genitourinary pathologists. | journal = Hum Pathol | volume = 37 | issue = 3 | pages = 292-7 | month = Mar | year = 2006 | doi = | PMID = 16613324 }}</ref><ref name=pmid10435561>{{Cite journal | last1 = Baisden | first1 = BL. | last2 = Kahane | first2 = H. | last3 = Epstein | first3 = JI. | title = Perineural invasion, mucinous fibroplasia, and glomerulations: diagnostic features of limited cancer on prostate needle biopsy. | journal = Am J Surg Pathol | volume = 23 | issue = 8 | pages = 918-24 | month = Aug | year = 1999 | doi = | PMID = 10435561 }}</ref> | '''Mucinous fibroplasia''', also '''collagenous micronodules''', is a finding seen in the [[prostate gland]] that is considered pathognomonic for [[prostate carcinoma]] by many genitourinary pathologists.<ref name=pmid16613324>{{Cite journal | last1 = Egevad | first1 = L. | last2 = Allsbrook | first2 = WC. | last3 = Epstein | first3 = JI. | title = Current practice of diagnosis and reporting of prostate cancer on needle biopsy among genitourinary pathologists. | journal = Hum Pathol | volume = 37 | issue = 3 | pages = 292-7 | month = Mar | year = 2006 | doi = | PMID = 16613324 }}</ref><ref name=pmid10435561>{{Cite journal | last1 = Baisden | first1 = BL. | last2 = Kahane | first2 = H. | last3 = Epstein | first3 = JI. | title = Perineural invasion, mucinous fibroplasia, and glomerulations: diagnostic features of limited cancer on prostate needle biopsy. | journal = Am J Surg Pathol | volume = 23 | issue = 8 | pages = 918-24 | month = Aug | year = 1999 | doi = | PMID = 10435561 }}</ref> | ||
==General== | ==General== | ||
*Considered pathognomonic by 64% of genitourinary pathologists in one survey with 64 respondents.<ref name=pmid16613324/> | *Considered pathognomonic by 64% of genitourinary pathologists in one survey with 64 respondents.<ref name=pmid16613324/> | ||
*Thought to arise from intraglandular mucin.{{fact}} | |||
==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
*Small collegneous-like nodules within (malignant) prostatic glands. | *Small collegneous-like nodules within (malignant) prostatic glands. | ||
===Images=== | |||
<gallery> | |||
Image: Mucinous fibroplasia -- high mag.jpg | CM - high mag. | |||
Image: Mucinous fibroplasia -- very high mag.jpg | CM - very high mag. | |||
Image: Mucinous fibroplasia - alt -- very high mag.jpg | CM - very high mag. | |||
</gallery> | |||
==See also== | ==See also== | ||
Latest revision as of 04:40, 5 April 2015
Mucinous fibroplasia, also collagenous micronodules, is a finding seen in the prostate gland that is considered pathognomonic for prostate carcinoma by many genitourinary pathologists.[1][2]
General
- Considered pathognomonic by 64% of genitourinary pathologists in one survey with 64 respondents.[1]
- Thought to arise from intraglandular mucin.[citation needed]
Microscopic
Features:
- Small collegneous-like nodules within (malignant) prostatic glands.
Images
CM - high mag.
CM - very high mag.
CM - very high mag.
See also
References
- ↑ 1.0 1.1 Egevad, L.; Allsbrook, WC.; Epstein, JI. (Mar 2006). "Current practice of diagnosis and reporting of prostate cancer on needle biopsy among genitourinary pathologists.". Hum Pathol 37 (3): 292-7. PMID 16613324.
- ↑ Baisden, BL.; Kahane, H.; Epstein, JI. (Aug 1999). "Perineural invasion, mucinous fibroplasia, and glomerulations: diagnostic features of limited cancer on prostate needle biopsy.". Am J Surg Pathol 23 (8): 918-24. PMID 10435561.