653
edits
Difference between revisions of "Nipple adenoma"
Jump to navigation
Jump to search
→Microscopic
| Line 44: | Line 44: | ||
==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
*Not encapsulated.<ref name=pmid2123505/> | |||
*Proliferation of epithelial and myoepithelial elements that extends into the breast stroma.<ref name=pmid2123505>{{Cite journal | title = Adenoma of Nipple. | journal = Br Med J | volume = 1 | issue = 5330 | pages = 563 | month = Mar | year = 1963 | doi = | PMID = 20789667 | PMC = 2123505 | url = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2123505/?page=1 }}</ref> | *Proliferation of epithelial and myoepithelial elements that extends into the breast stroma.<ref name=pmid2123505>{{Cite journal | title = Adenoma of Nipple. | journal = Br Med J | volume = 1 | issue = 5330 | pages = 563 | month = Mar | year = 1963 | doi = | PMID = 20789667 | PMC = 2123505 | url = http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2123505/?page=1 }}</ref> | ||
*Arborising papillomatous epithelial proliferation within duct | *Arborising papillomatous epithelial proliferation within duct | ||
*Papillae have fibrovascular cores. | *(Papillae have fibrovascular cores) at least as far as I can see but not according to Stanford. | ||
*Florid epithelial hyperplasia can be seen | *Florid epithelial hyperplasia can be seen | ||
*Can see haphazard arrangement of proliferating tubular structures | *Can see haphazard arrangement of proliferating tubular structures | ||
Notes: | Notes: | ||
*Lacks true fibrovascular cores.<ref>URL: [http://surgpathcriteria.stanford.edu/breast/nippleadenoma/printable.html http://surgpathcriteria.stanford.edu/breast/nippleadenoma/printable.html]. Accessed on: 6 August 2011.</ref> | *Lacks true fibrovascular cores.<ref>URL: [http://surgpathcriteria.stanford.edu/breast/nippleadenoma/printable.html http://surgpathcriteria.stanford.edu/breast/nippleadenoma/printable.html]. Accessed on: 6 August 2011.</ref> | ||
*Focal necrosis may be present.<ref name=Ref_APBR307>{{Ref APBR|307 Q16}}</ref> | *Focal necrosis may be present.<ref name=Ref_APBR307>{{Ref APBR|307 Q16}}</ref> | ||
| Line 61: | Line 60: | ||
**Often deeper - one should '''not''' see skin in the histologic section. | **Often deeper - one should '''not''' see skin in the histologic section. | ||
*Syringomatous adenoma | *Syringomatous adenoma | ||
*Intraductal carcinoma - | *Intraductal carcinoma - the proliferation in nipple adenoma should be no more atypical than that seen with usual intraductal hyperplasia or intraductal papillomatosis. Cribriforming glands should be absent | ||
*Invasive ductal carcinoma - IHC is useful (see below) the ducts should all be lined by myoepithelium. | *Invasive ductal carcinoma - IHC is useful (see below) the ducts should all be lined by myoepithelium. | ||