Difference between revisions of "Anus"

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Anus (view source)

Revision as of 17:56, 19 March 2015

1,870 bytes removed ,  17:56, 19 March 2015
→‎Anal squamous cell carcinoma: split out
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*[[AKA]] ''anal squamous carcinoma''.
*[[AKA]] ''anal squamous carcinoma''.
*[[AKA]] ''squamous cell carcinoma of the anus''.
*[[AKA]] ''squamous cell carcinoma of the anus''.
===General===
{{Main|Anal squamous cell carcinoma}}
*Most common form of anal cancer.
 
Risk factors:<ref name=pmid23806153>{{Cite journal  | last1 = Kutlubay | first1 = Z. | last2 = Engin | first2 = B. | last3 = Zara | first3 = T. | last4 = Tüzün | first4 = Y. | title = Anogenital malignancies and premalignancies: Facts and controversies. | journal = Clin Dermatol | volume = 31 | issue = 4 | pages = 362-73 | month =  | year =  | doi = 10.1016/j.clindermatol.2013.01.003 | PMID = 23806153 }}</ref>
*Men who have sex with men.
*Immunosuppressed.
*[[HIV]] infection.
===Microscopic===
Features:
*See ''[[squamous cell carcinoma]]''.
 
<gallery>
Image:Anus SquamousCellCarcinoma SCC NonKeratinizing AIA SCCIS CTR.jpg|Anus Squamous Cell Carcinoma (Non Keratinizing) - (SKB)
Image:Anus SquamousCellCarcinoma SCC NonKeratinizing MP CTR.jpg|Anus Squamous Cell Carcinoma (Non Keratinizing) - (SKB)
Image:Anus SquamousCellCarcinoma SCC NonKeratinizing MP4 CTR.jpg|Anus Squamous Cell Carcinoma (Non Keratinizing or shall we say poorly keratinizing as there are squamatized nests focally at high power) - (SKB)
</gallery>
DDx:
*[[Anal gland adenocarcinoma]].
*Poorly differentiated [[rectal adenocarcinoma]].
 
===IHC===
*p16 +ve.<ref name=pmid23105122/>
*CDX2 -ve/+ve.
**May be useful to differentiate from vulva and penis.<ref name=pmid23105122>{{Cite journal  | last1 = Gunia | first1 = S. | last2 = Koch | first2 = S. | last3 = May | first3 = M. | title = Is CDX2 immunostaining useful for delineating anorectal from penile/vulvar squamous cancer in the setting of squamous cell carcinoma with clinically unknown primary site presenting with histologically confirmed inguinal lymph node metastasis? | journal = J Clin Pathol | volume = 66 | issue = 2 | pages = 109-12 | month = Feb | year = 2013 | doi = 10.1136/jclinpath-2012-201138 | PMID = 23105122 }}</ref>
 
===Sign out===
<pre>
RECTUM, DISTAL, BIOPSY:
- INVASIVE SQUAMOUS CELL CARCINOMA.
</pre>


==Anal gland adenocarcinoma==
==Anal gland adenocarcinoma==
Michael
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