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Difference between revisions of "Tubulocystic carcinoma of the kidney"
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Tubulocystic carcinoma of the kidney (view source)
Revision as of 03:11, 13 February 2015
, 03:11, 13 February 2015+PaRCC
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| Micro = cysts of variable size lined by a single layer of epithelium that has a cuboidal, flat, or hobnail morphology, eosinophilic cytoplasm, large nuclei with prominent nucleoli, +/-fibrotic stroma | | Micro = cysts of variable size lined by a single layer of epithelium that has a cuboidal, flat, or hobnail morphology, eosinophilic cytoplasm, large nuclei with prominent nucleoli, +/-fibrotic stroma | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[renal oncocytoma]], [[cystic nephroma]]/[[mixed epithelial and stromal tumour]], [[multilocular cystic renal cell carcinoma]] | | LMDDx = [[papillary renal cell carcinoma]], [[renal oncocytoma]], [[cystic nephroma]]/[[mixed epithelial and stromal tumour]], [[multilocular cystic renal cell carcinoma]] | ||
| Stains = | | Stains = | ||
| IHC = CD10 +ve, RCC +ve, vimentin +ve, AMACR +ve | | IHC = CD10 +ve, RCC +ve, vimentin +ve, AMACR +ve | ||
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*Males:Females ~ 7:1.<ref name=pmid19011562/> | *Males:Females ~ 7:1.<ref name=pmid19011562/> | ||
*Prognosis - probably favourable.<ref name=pmid19011562/> | *Prognosis - probably favourable.<ref name=pmid19011562/> | ||
*Thought to be related to [[papillary renal cell carcinoma]].<ref name=pmid19898225>{{Cite journal | last1 = Zhou | first1 = M. | last2 = Yang | first2 = XJ. | last3 = Lopez | first3 = JI. | last4 = Shah | first4 = RB. | last5 = Hes | first5 = O. | last6 = Shen | first6 = SS. | last7 = Li | first7 = R. | last8 = Yang | first8 = Y. | last9 = Lin | first9 = F. | title = Renal tubulocystic carcinoma is closely related to papillary renal cell carcinoma: implications for pathologic classification. | journal = Am J Surg Pathol | volume = 33 | issue = 12 | pages = 1840-9 | month = Dec | year = 2009 | doi = 10.1097/PAS.0b013e3181be22d1 | PMID = 19898225 }}</ref> | |||
==Gross== | ==Gross== | ||
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DDx: | DDx: | ||
*[[Papillary renal cell carcinoma]] (oncocytic variant). | |||
*[[Renal oncocytoma]]. | *[[Renal oncocytoma]]. | ||
*[[Cystic nephroma]]/[[Mixed epithelial and stromal tumour]]. | *[[Cystic nephroma]]/[[Mixed epithelial and stromal tumour]]. | ||