Difference between revisions of "Multilocular cystic renal neoplasm of low malignant potential"
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==Gross== | ==Gross== | ||
Features:<ref name=Ref_WMSP292>{{Ref WMSP|292}}</ref> | Features:<ref name=Ref_WMSP292>{{Ref WMSP|292}}</ref> | ||
* | *Completely cystic with thin septa. | ||
**No solid nodules - required for diagnosis.<ref name=pmid9503503/> | |||
*Well circumscribed. | *Well circumscribed. | ||
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==Microscopic== | ==Microscopic== | ||
Features:<ref name=Ref_WMSP292>{{Ref WMSP|292}}</ref> | Features:<ref name=Ref_WMSP292>{{Ref WMSP|292}}</ref><ref name=pmid9503503>{{Cite journal | last1 = Eble | first1 = JN. | last2 = Bonsib | first2 = SM. | title = Extensively cystic renal neoplasms: cystic nephroma, cystic partially differentiated nephroblastoma, multilocular cystic renal cell carcinoma, and cystic hamartoma of renal pelvis. | journal = Semin Diagn Pathol | volume = 15 | issue = 1 | pages = 2-20 | month = Feb | year = 1998 | doi = | PMID = 9503503 }}</ref> | ||
* | *Thin septa with (polygonal) cells with a clear cytoplasm - required. | ||
* | *Fibrous capsule (surrounds tumour) - required. | ||
*+/-Calcification (common). | *+/-Calcification (common). | ||
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==References== | ==References== | ||
{{Reflist| | {{Reflist|2}} | ||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Kidney tumours]] | [[Category:Kidney tumours]] | ||
Revision as of 05:42, 5 January 2015
Multilocular cystic renal cell carcinoma, abbreviated MCRCC, is a rare kidney tumour.
It is also known as multilocular clear cell renal cell carcinoma.[1]
As the behaviour of the tumour is very good, it has be proposed that this entity be renamed multilocular cystic renal cell neoplasms of low malignant potential.[2]
General
Gross
Features:[3]
- Completely cystic with thin septa.
- No solid nodules - required for diagnosis.[5]
- Well circumscribed.
Note:
- This tumour, radiologically, can often be separated from other cystic tumours.[6]
Microscopic
- Thin septa with (polygonal) cells with a clear cytoplasm - required.
- Fibrous capsule (surrounds tumour) - required.
- +/-Calcification (common).
DDx:
- Cystic renal disease with macrophages in the septa.
- Cystic clear cell renal cell carcinoma.
- Tubulocystic carcinoma.
IHC
- EMA +ve.
- Keratins +ve.
- CD68 -ve.
See also
References
- ↑ Chowdhury, AR.; Chakraborty, D.; Bhattacharya, P.; Dey, RK. (Apr 2013). "Multilocular cystic renal cell carcinoma a diagnostic dilemma: A case report in a 30-year-old woman.". Urol Ann 5 (2): 119-21. doi:10.4103/0974-7796.110012. PMID 23798872.
- ↑ Montironi, R.; Mazzucchelli, R.; Scarpelli, M.; Lopez-Beltran, A.; Cheng, L. (Dec 2013). "Update on selected renal cell tumors with clear cell features. With emphasis on multilocular cystic clear cell renal cell carcinoma.". Histol Histopathol 28 (12): 1555-66. PMID 23893851.
- ↑ 3.0 3.1 3.2 Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 292. ISBN 978-0781765275.
- ↑ Agarwal, S.; Agrawal, U.; Mohanty, NK.; Saxena, S. (Mar 2011). "Multilocular cystic renal cell carcinoma: a case report of a rare entity.". Arch Pathol Lab Med 135 (3): 290-2. doi:10.1043/2010-0243-LE.1. PMID 21366448.
- ↑ 5.0 5.1 Eble, JN.; Bonsib, SM. (Feb 1998). "Extensively cystic renal neoplasms: cystic nephroma, cystic partially differentiated nephroblastoma, multilocular cystic renal cell carcinoma, and cystic hamartoma of renal pelvis.". Semin Diagn Pathol 15 (1): 2-20. PMID 9503503.
- ↑ You, D.; Shim, M.; Jeong, IG.; Song, C.; Kim, JK.; Ro, JY.; Hong, JH.; Ahn, H. et al. (Jul 2011). "Multilocular cystic renal cell carcinoma: clinicopathological features and preoperative prediction using multiphase computed tomography.". BJU Int. doi:10.1111/j.1464-410X.2011.10247.x. PMID 21722289.