Difference between revisions of "Multilocular cystic renal neoplasm of low malignant potential"

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It is also known as '''multilocular clear cell renal cell carcinoma'''.<ref name=pmid23798872>{{Cite journal  | last1 = Chowdhury | first1 = AR. | last2 = Chakraborty | first2 = D. | last3 = Bhattacharya | first3 = P. | last4 = Dey | first4 = RK. | title = Multilocular cystic renal cell carcinoma a diagnostic dilemma: A case report in a 30-year-old woman. | journal = Urol Ann | volume = 5 | issue = 2 | pages = 119-21 | month = Apr | year = 2013 | doi = 10.4103/0974-7796.110012 | PMID = 23798872 }}</ref>
It is also known as '''multilocular clear cell renal cell carcinoma'''.<ref name=pmid23798872>{{Cite journal  | last1 = Chowdhury | first1 = AR. | last2 = Chakraborty | first2 = D. | last3 = Bhattacharya | first3 = P. | last4 = Dey | first4 = RK. | title = Multilocular cystic renal cell carcinoma a diagnostic dilemma: A case report in a 30-year-old woman. | journal = Urol Ann | volume = 5 | issue = 2 | pages = 119-21 | month = Apr | year = 2013 | doi = 10.4103/0974-7796.110012 | PMID = 23798872 }}</ref>
As the behaviour of the tumour is very good, it has be proposed that this entity be renamed '''multilocular cystic renal cell neoplasms of low malignant potential'''.<ref name=pmid23893851>{{Cite journal  | last1 = Montironi | first1 = R. | last2 = Mazzucchelli | first2 = R. | last3 = Scarpelli | first3 = M. | last4 = Lopez-Beltran | first4 = A. | last5 = Cheng | first5 = L. | title = Update on selected renal cell tumors with clear cell features. With emphasis on multilocular cystic clear cell renal cell carcinoma. | journal = Histol Histopathol | volume = 28 | issue = 12 | pages = 1555-66 | month = Dec | year = 2013 | doi =  | PMID = 23893851 }}</ref>


==General==
==General==
*No recurrences or metastasis in the literature.<ref name=Ref_WMSP292>{{Ref WMSP|292}}</ref>
*No recurrences or metastasis in the literature.<ref name=Ref_WMSP292>{{Ref WMSP|292}}</ref>
**This makes one wonder... is it really cancer.
*Case report rare.<ref name=pmid21366448>{{Cite journal  | last1 = Agarwal | first1 = S. | last2 = Agrawal | first2 = U. | last3 = Mohanty | first3 = NK. | last4 = Saxena | first4 = S. | title = Multilocular cystic renal cell carcinoma: a case report of a rare entity. | journal = Arch Pathol Lab Med | volume = 135 | issue = 3 | pages = 290-2 | month = Mar | year = 2011 | doi = 10.1043/2010-0243-LE.1 | PMID = 21366448 }}</ref>
*Case report rare.<ref name=pmid21366448>{{Cite journal  | last1 = Agarwal | first1 = S. | last2 = Agrawal | first2 = U. | last3 = Mohanty | first3 = NK. | last4 = Saxena | first4 = S. | title = Multilocular cystic renal cell carcinoma: a case report of a rare entity. | journal = Arch Pathol Lab Med | volume = 135 | issue = 3 | pages = 290-2 | month = Mar | year = 2011 | doi = 10.1043/2010-0243-LE.1 | PMID = 21366448 }}</ref>


Revision as of 02:32, 5 January 2015

Multilocular cystic renal cell carcinoma, abbreviated MCRCC, is a rare kidney tumour.

It is also known as multilocular clear cell renal cell carcinoma.[1]

As the behaviour of the tumour is very good, it has be proposed that this entity be renamed multilocular cystic renal cell neoplasms of low malignant potential.[2]

General

  • No recurrences or metastasis in the literature.[3]
  • Case report rare.[4]

Gross

Features:[3]

  • Cystic with thin septa.
  • Well circumscribed.

Note:

  • This tumour, radiologically, can often be separated from other cystic tumours.[5]

Microscopic

Features:[3]

  • Polygonal cells within the septa.
  • Clear cytoplasm.
  • +/-Calcification (common).

DDx:

IHC

  • EMA +ve.
  • Keratins +ve.
  • CD68 -ve.

See also

References

  1. ↑ Chowdhury, AR.; Chakraborty, D.; Bhattacharya, P.; Dey, RK. (Apr 2013). "Multilocular cystic renal cell carcinoma a diagnostic dilemma: A case report in a 30-year-old woman.". Urol Ann 5 (2): 119-21. doi:10.4103/0974-7796.110012. PMID 23798872.
  2. ↑ Montironi, R.; Mazzucchelli, R.; Scarpelli, M.; Lopez-Beltran, A.; Cheng, L. (Dec 2013). "Update on selected renal cell tumors with clear cell features. With emphasis on multilocular cystic clear cell renal cell carcinoma.". Histol Histopathol 28 (12): 1555-66. PMID 23893851.
  3. ↑ 3.0 3.1 3.2 Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 292. ISBN 978-0781765275.
  4. ↑ Agarwal, S.; Agrawal, U.; Mohanty, NK.; Saxena, S. (Mar 2011). "Multilocular cystic renal cell carcinoma: a case report of a rare entity.". Arch Pathol Lab Med 135 (3): 290-2. doi:10.1043/2010-0243-LE.1. PMID 21366448.
  5. ↑ You, D.; Shim, M.; Jeong, IG.; Song, C.; Kim, JK.; Ro, JY.; Hong, JH.; Ahn, H. et al. (Jul 2011). "Multilocular cystic renal cell carcinoma: clinicopathological features and preoperative prediction using multiphase computed tomography.". BJU Int. doi:10.1111/j.1464-410X.2011.10247.x. PMID 21722289.
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