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Difference between revisions of "Enteropathy-associated T-cell lymphoma"
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Enteropathy-associated T-cell lymphoma (view source)
Revision as of 07:55, 20 December 2014
, 07:55, 20 December 2014+infobox
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Enteropathy-associated_T_cell_lymphoma_-_low_mag.jpg | |||
| Width = | |||
| Caption = Enteropathy-associated T cell lymphoma. [[H&E stain]]. | |||
| Synonyms = enteropathy-type T-cell lymphoma | |||
| Micro = large ''or'' medium-sized lymphoid cells in the mucosa and submucosa | |||
| Subtypes = | |||
| LMDDx = | |||
| Stains = | |||
| IHC = CD3 +ve, CD5 -ve, CD8 -ve/+ve, CD56 -ve/+ve, CD30 +ve | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[duodenum]] | |||
| Assdx = [[celiac disease]] | |||
| Syndromes = | |||
| Clinicalhx = history of celiac disease | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Enteropathy-associated T-cell lymphoma''', abbreviated '''EATL''', is an uncommon type of [[lymphoma]] associated with [[celiac disease]]. | '''Enteropathy-associated T-cell lymphoma''', abbreviated '''EATL''', is an uncommon type of [[lymphoma]] associated with [[celiac disease]]. | ||
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==Microscopic== | ==Microscopic== | ||
Features:<ref name=pmid21323966>{{Cite journal | last1 = Takeshita | first1 = M. | last2 = Nakamura | first2 = S. | last3 = Kikuma | first3 = K. | last4 = Nakayama | first4 = Y. | last5 = Nimura | first5 = S. | last6 = Yao | first6 = T. | last7 = Urabe | first7 = S. | last8 = Ogawara | first8 = S. | last9 = Yonemasu | first9 = H. | title = Pathological and immunohistological findings and genetic aberrations of intestinal enteropathy-associated T cell lymphoma in Japan. | journal = Histopathology | volume = 58 | issue = 3 | pages = 395-407 | month = Feb | year = 2011 | doi = 10.1111/j.1365-2559.2011.03768.x | PMID = 21323966 }}</ref> | Features:<ref name=pmid21323966>{{Cite journal | last1 = Takeshita | first1 = M. | last2 = Nakamura | first2 = S. | last3 = Kikuma | first3 = K. | last4 = Nakayama | first4 = Y. | last5 = Nimura | first5 = S. | last6 = Yao | first6 = T. | last7 = Urabe | first7 = S. | last8 = Ogawara | first8 = S. | last9 = Yonemasu | first9 = H. | title = Pathological and immunohistological findings and genetic aberrations of intestinal enteropathy-associated T cell lymphoma in Japan. | journal = Histopathology | volume = 58 | issue = 3 | pages = 395-407 | month = Feb | year = 2011 | doi = 10.1111/j.1365-2559.2011.03768.x | PMID = 21323966 }}</ref> | ||
* | *Abundant large ''or'' medium-sized lymphoid cells in the mucosa and submucosa. | ||
**Large-sized cells ~ 2x RBC diameter = type 1. | **Large-sized cells ~ 2x RBC diameter = type 1. | ||
**Medium sized cells ~ 1.5x RBC diameter = type 2. | **Medium sized cells ~ 1.5x RBC diameter = type 2. | ||
*Intestinal epithelium usually preserved. | *Intestinal epithelium usually preserved. | ||
DDx: | |||
*Other types of lymphoma, e.g. [[DLBCL]]. | |||
===Image=== | ===Image=== | ||
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==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Lymphoma]] | [[Category:Lymphoma]] | ||